O7635
Anti-Osteopontin antibody produced in goat
affinity isolated antibody, lyophilized powder
Sinonimo/i:
Anti-OPN
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About This Item
Prodotti consigliati
Origine biologica
goat
Livello qualitativo
Coniugato
unconjugated
Forma dell’anticorpo
affinity isolated antibody
Tipo di anticorpo
primary antibodies
Clone
polyclonal
Stato
lyophilized powder
Reattività contro le specie
mouse
tecniche
capture ELISA: 0.2-0.8 μg/mL
immunohistochemistry: 5-15 μg/mL using mouse thymus tissue sections
neutralization: 1-3 μg/mL
western blot: 0.1-0.2 μg/mL
N° accesso UniProt
Temperatura di conservazione
−20°C
modifica post-traduzionali bersaglio
unmodified
Informazioni sul gene
mouse ... Spp1(20750)
Descrizione generale
The OPN (osteopontin) gene is mapped to mouse chromosome 5 E5 and codes for secreted phosphoprotein 1 and is mostly expressed in bone tissue.
Immunogeno
purified recombinant mouse osteopontin expressed in NSO cells.
Azioni biochim/fisiol
Osteopontin (OPN) serves as a ligand to a number of integrin receptors which are associated with cell motility, chemotaxis, invasion and cell survival. Upregulation of OPN gene is observed in tumors such as colorectal carcinomas, breast cancer and contributes to its pathogenesis. OPN is associated with obesity by mediating adipocyte inflammation and insulin resistance upon macrophage activation. OPN functions as an effector molecule in extracellular signalling and promotes fibrosis and myocyte growth.
Stato fisico
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
Risultati analitici
Neutralizes the biological activity of recombinant mouse osteopontin using 293 cells.
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
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