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Merck
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Documenti

N4007

Sigma-Aldrich

N-Nitroso-N-methylbutylamine

Sinonimo/i:

Methylbutylnitrosamine

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About This Item

Formula empirica (notazione di Hill):
C5H12N2O
Numero CAS:
7068-83-9
Peso molecolare:
116.16
Numero MDL:
MFCD00056645
Codice UNSPSC:
12352116
ID PubChem:
24897361
NACRES:
NA.25

Forma fisica

liquid

Densità

0.93 g/mL (lit.)

Temperatura di conservazione

2-8°C

Stringa SMILE

CCCCN(C)N=O

InChI

1S/C5H12N2O/c1-3-4-5-7(2)6-8/h3-5H2,1-2H3
PKTSCJXWLVREKX-UHFFFAOYSA-N

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Confezionamento

Bulk package

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Indicazioni di pericolo

H301,H310 + H330,H350

Classi di pericolo

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 3 Oral - Carc. 1B

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Sigma-Aldrich

73861

N-Nitrosodiethylamine

Supelco

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48320-U

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Supelco

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1-Nitrosopiperidine solution

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Sigma-Aldrich

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Supelco

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EPA 521 Nitrosamine Mix

K E Appel et al.
Carcinogenesis, 7(4), 659-663 (1986-04-01)
To demonstrate whether there are any pathways of nitrite formation from N-nitrosamines other than reductive denitrosation by cytochrome P-450 we performed the following experiments. An esterified alpha-hydroxylated nitrosamine was incubated in a microsomal system to test if nitrite generation is
J G Farrelly et al.
Cancer research, 42(6), 2105-2109 (1982-06-01)
With the use of rat liver preparations, the in vitro microsomal metabolism of methylethylnitrosamine, methyl-n-butylnitrosamine, and methyl(2-phenylethyl)nitrosamine labeled with deuterium in the methyl and alpha-methylene positions has been compared with that of the parent (unlabeled) compounds. All three forms of
M Lee et al.
Cancer research, 49(6), 1470-1474 (1989-03-15)
Metabolic activation may be a key step in determining the tissue specificity of carcinogenic nitrosamines. In previous work, we characterized P450IIE1 (an acetone/ethanol-inducible form of cytochrome P-450) as the major enzyme for the metabolic activation of N-nitrosodimethylamine. In this work
T Gichner et al.
Mutagenesis, 1(2), 107-109 (1986-03-01)
The organic solvents dimethylsulphoxide (DMSO), acetone, ethanol and dimethylformamide inhibited the mutagenic activity of the promutagens dimethylnitrosamine and methylbutylnitrosamine in a higher plant Arabidopsis thaliana. In contrast, the direct-acting mutagens N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and N-methyl-N-nitrosourea (MNU) were not affected by the
Q Huang et al.
Cancer letters, 69(2), 107-116 (1993-04-30)
We studied the metabolism of methyl-n-butyl-nitrosamine (MBN), a carcinogen for the rat esophagus and liver. The 2-, 3- and 4-hydroxy derivatives were identified as new metabolites of MBN. In studies on tissue slices freshly removed from MRC-Wistar rats, MBN metabolism
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