MAK156
Fatty Acid Uptake Kit
sufficient for 100 fluorometric tests
Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
About This Item
Prodotti consigliati
impiego
sufficient for 100 fluorometric tests
Metodo di rivelazione
fluorometric
Malattie correlate
endocrinological disorders, diabetes; gastrointestinal diseases; cancer
Temperatura di conservazione
−20°C
Categorie correlate
Descrizione generale
Fatty acids are critical for many biological processes including energy metabolism and the synthesis of structural cellular components. The facilitated uptake of fatty acids, presumably through fatty acid transport proteins, is thought to be regulated at multiple levels. The dysregulation of fatty acid uptake may contribute to diseases such as obesity, type 2 diabetes, and hepatic steatosis.
Compatibilità
This kit is suitable for the measurement of fatty acid uptake in cells containing fatty acid transporters
Principio
This kit is provides a simple and sensitive method for the measurement of fatty acid uptake in cells containing fatty acid transporters. This kit uses a proprietary dodecanoic acid fluorescent fatty acid substrate whose uptake into cells result in an increase in fluorescence intensity (λex = 485/λem = 515 nm).
Codice della classe di stoccaggio
10 - Combustible liquids
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Stephanie Kim et al.
Environmental health perspectives, 129(7), 77006-77006 (2021-07-30)
Chemicals in disparate structural classes activate specific subsets of the transcriptional programs of peroxisome proliferator-activated receptor-γ (PPARγ) to generate adipocytes with distinct phenotypes. Our objectives were to a) establish a novel classification method to predict PPARγ ligands and modifying chemicals;
Mona S Nilsen et al.
Diabetes, 69(9), 1903-1916 (2020-06-27)
Circulating branched-chain amino acids (BCAAs) associate with insulin resistance and type 2 diabetes. 3-Hydroxyisobutyrate (3-HIB) is a catabolic intermediate of the BCAA valine. In this study, we show that in a cohort of 4,942 men and women, circulating 3-HIB is
Stephanie Kim et al.
Archives of toxicology, 94(9), 3087-3103 (2020-07-20)
Triphenyl phosphate (TPhP) is an environmental PPARγ ligand, and growing evidence suggests that it is a metabolic disruptor. We have shown previously that the structurally similar ligand, tributyltin, does not induce brite adipocyte gene expression. Here, using in vivo and
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