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M8819

Sigma-Aldrich

Mannide monooleate

from plant

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About This Item

Numero CAS:
9049-98-3
Numero MDL:
MFCD03840565
Codice UNSPSC:
12352201
ID PubChem:
329818072
NACRES:
NA.25
Prezzi e disponibilità al momento non sono disponibili

Origine biologica

plant

Livello qualitativo

200

Stato

liquid

Colore

dark brown

Temperatura di conservazione

room temp

Stringa SMILE

CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)C1OC[C@H](O)[C@H]1O

InChI

1S/C24H44O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(27)29-19-21(26)24-23(28)20(25)18-30-24/h9-10,20-21,23-26,28H,2-8,11-19H2,1H3/b10-9-/t20-,21+,23+,24+/m0/s1
NWGKJDSIEKMTRX-AAZCQSIUSA-N

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910708

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assay

≥80%

assay

≥80%

assay

≥90%

assay

≥90%

form

powder

form

powder

form

powder

form

powder

color

dark gray

color

dark gray

color

dark gray

color

dark gray

particle size

≤100 μm

particle size

≤200 μm

particle size

≤100 μm

particle size

≤40 μm

Descrizione generale

Mannide monooleate is a lipohilic surfactant. [1] It is also a non-ionic surface active emulsifier.

Applicazioni

Mannide monooleate has been used in a study to assess Freund′s incomplete adjuvant emulsion system, which is used in vaccine therapy. [2] It has also been used in a study to investigate the metabolic fate of mineral oil adjuvants using 14C-labeled tracers. [3]

Azioni biochim/fisiol

Mannide monooleate is an emulsifying agent utilized in Freund′s incomplete adjuvant, although reactogenicity is an issue with human use.

Altre note

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves

  • Scheda delle specifiche

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    Certificati d'analisi (COA)

    Lot/Batch Number
    MKCQ6302
    MKCQ4387
    MKCQ2491
    MKCQ1440
    MKCP8541

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    Metabolic fate of mineral oil adjuvants using 14C-labeled tracers. II. Mannide monooleate.
    J N Bollinger
    Journal of pharmaceutical sciences, 59(8), 1088-1092 (1970-08-01)
    R O Williams et al.
    Drug development and industrial pharmacy, 24(2), 157-162 (2004-12-21)
    Freund's Incomplete Adjuvant (FIA), which is used in vaccine therapy, is a water-in-oil emulsion delivery system consisting of an aqueous internal phase containing an antigenic protein dispersed in an external phase containing a mixture of mannide monooleate and light mineral
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    Expert review of vaccines, 1(1), 111-118 (2003-08-12)
    The development of adjuvants will represent a major challenge for this century. Indeed the need for safer vaccines leads to the development of a new generation of antigens like synthetic peptide, recombinant proteins or even vectored DNA. However, this is
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    The Plasmodium protein Cell-traversal protein for ookinetes and sporozoites (CelTOS) plays an important role in cell traversal of host cells in both, mosquito and vertebrates, and is required for successful malaria infections. CelTOS is highly conserved among the Plasmodium species
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    To compare the ability of a native and a recombinant preparation of the major outer membrane protein of Chlamydia trachomatis mouse pneumonitis (MoPn; Ct-nMOMP and Ct-rMOMP) to protect against an intranasal (i.n.) challenge, BALB/c mice were vaccinated by the intramuscular
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