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M6045

Sigma-Aldrich

2-Methyl-4-isothiazolin-3-one hydrochloride

≥99%

Sinonimo/i:

MIT, Methylisothiazolinone hydrochloride

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About This Item

Formula empirica (notazione di Hill):
C4H5NOS · HCl
Numero CAS:
26172-54-3
Peso molecolare:
151.61
Beilstein:
3993054
Numero CE:
247-499-3
Numero MDL:
MFCD06804636
Codice UNSPSC:
51102829
ID PubChem:
24897073
NACRES:
NA.76

Livello qualitativo

200

Saggio

≥99%

Modalità d’azione

protein synthesis | interferes

Temperatura di conservazione

2-8°C

Stringa SMILE

Cl[H].CN1SC=CC1=O

InChI

1S/C4H5NOS.ClH/c1-5-4(6)2-3-7-5;/h2-3H,1H3;1H
SJXPQSRCFCPWQQ-UHFFFAOYSA-N

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Descrizione generale

2-Methyl-4-isothiazolin-3-one hydrochloride (MIT) is a derivative of the synthetic isothiazolinone.

Applicazioni

Methylisothiazolinone (MIT) has been used:
  • as a cytotoxic substance to investigate its effect on bronchial epithelial cells (BEAS-2B cells) and its role in apoptotic cell death
  • to study the effects of tyrosine phosphorylation on focal adhesion kinase (FAK) activity in the development of neural axons and dendrites

Azioni biochim/fisiol

2-Methyl-4-isothiazolin-3-one hydrochloride (MIT) is a skin sensitizer known to cause contact dermatitis and allergy. It is extensively used in the cosmetic industry as a preservative. MIT is a neurotoxin and its prolonged exposure may lead to neuronal death and inhibition of neurite outgrowth.

Avvertenze

Danger

Indicazioni di pericolo

H301,H314,H317,H410

Classi di pericolo

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1

Rischi supp

EUH071

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Supelco

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Sigma-Aldrich

687677

Benzisothiazolinone-15N

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