48912-U
ProClin™ 300
ProClin™ preservative for use in IVD manufacturing, pkg of 50 mL, CMIT/MIT 3 %
Sinonimo/i:
3% solution of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-Methyl-4-isothiazolin-3-one
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About This Item
Codice UNSPSC:
12352201
NACRES:
NA.21
Prodotti consigliati
Stato
liquid
Durata
3 yr
contiene
Alkyl Carboxylate
Composizione
CMIT/MIT, 3%
Confezionamento
pkg of 50 mL
Parametri
<45 °C operating temperature
Colore
colorless to light yellow
Matrice
Modified glycol
Intervallo di pH d’impiego
2.5-8.5
pH
4.1 (100 g/L)
P. ebollizione
189 °C
Punto di fusione
-40 °C
Solubilità
water: soluble
Densità
1.03 g/cm3
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Descrizione generale
ProClin™ preservatives are water-soluble preparations of biocides that are generally used to increase the shelf life of reagents. ProClin™ 300 comprises of 3% of 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT) and 2-methyl-4-isothiazloin-3-one (MIT) in a salt-free proprietary glycol containing an alkly carboxylate stabilizer. It has a recommended working pH range as 2.5 - 8.5.
Applicazioni
For use in IVD Manufacturing
ProClin™ 300 is suitable for preparation of different buffers like ELISA buffer, sample and substrate dilution buffers for Single-Molecule Arrays (Simoa assay) and Immunoenzymatic assay. Additionally, Proclin™ may be used in preparing storage buffer to store beads coupled with coronavirus nucleocapsid protein for the serological multiplex assay.
ProClin™ biocides preservatives are immediately microstatic upon contact with microbial organisms as a result of their ability to quickly penetrate cell membranes and inhibit specific enzymes crucial to cellular respiration. Multiple specific sites of ProClin™ toxicity prevent microorganisms from developing high levels of resistance, making ProClin™ highly efficient even over extended storage periods of your IVD components.
Azioni biochim/fisiol
ProClin™ products contain active substances like CMIT and MIT which inhibit the Krebs cycle at four different check points, the enzymes pyruvate dehydrogenase, α-ketoglutarate dehydrogenase, succinate dehydrogenase, and NADH dehydrogenase. The inhibition of Krebs cycle leads to effective broad-spectrum biocidal activity against bacteria, fungi, and yeast.
Note legali
ProClin is a trademark of LANXESS Corp.
Esclusione di responsabilità
The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada′s Pest Management Regulatory Agency, Turkey′s Biocidal Products Regulation, Korea′s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.
Avvertenze
Danger
Indicazioni di pericolo
Classi di pericolo
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
Codice della classe di stoccaggio
8A - Combustible corrosive hazardous materials
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
244.4 °F - closed cup
Punto d’infiammabilità (°C)
118 °C - closed cup
Dispositivi di protezione individuale
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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