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Key Documents

Altri documenti

M2892

Sigma-Aldrich

Methylphenidate hydrochloride

Sinonimo/i:

threo-Methyl α-phenyl-α-(2-piperidyl)acetate hydrochloride, Ritalin hydrochloride

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About This Item

Formula empirica (notazione di Hill):
C14H19NO2 · HCl
Numero CAS:
298-59-9
Peso molecolare:
269.77
Numero CE:
206-065-3
Numero MDL:
MFCD00058191
Codice UNSPSC:
12352200
ID PubChem:
24896775
NACRES:
NA.77

Livello qualitativo

200

Controllo stupefacenti

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

applicazioni

forensics and toxicology

Ideatore

Johnson & Johnson

Stringa SMILE

Cl[H].COC(=O)C(C1CCCCN1)c2ccccc2

InChI

1S/C14H19NO2.ClH/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12;/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3;1H
JUMYIBMBTDDLNG-UHFFFAOYSA-N

Informazioni sul gene

human ... SLC6A2(6530) , SLC6A3(6531)

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Azioni biochim/fisiol

CNS stimulant; releases catecholamines; potent inhibitor of dopamine reuptake

Caratteristiche e vantaggi

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Applicazioni

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Exclamation markHealth hazard
GHS07,GHS08

Avvertenze

Danger

Indicazioni di pericolo

H302 - H334

Classi di pericolo

Acute Tox. 4 Oral - Resp. Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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The prescribed use of methylphenidate (Ritalin) in the treatment of attention deficit hyperactivity disorder has risen dramatically in recent years. The relative roles of dopamine, norepinephrine, and serotonin in the therapeutic action of these drugs was assessed by comparing the
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Developmental medicine and child neurology, 55(7), 654-660 (2013-03-14)
Difficult-to-treat epilepsies and attention-deficit-hyperactivity disorder (ADHD) often co-occur. Because of concerns about the use of stimulants in children with this comorbidity, the impact of ADHD treatment on seizure frequency and severity is not known. This pilot study evaluated the safety
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Canadian journal of psychiatry. Revue canadienne de psychiatrie, 58(11), 632-639 (2013-11-20)
Examine the short-term (acute) effects of methylphenidate (MPH) on math performance in children with attention-deficit hyperactivity disorder (ADHD) and what factors predict improvement in math performance. One hundred ninety-eight children with ADHD participated in a double-blind, placebo-controlled, randomized crossover MPH
Pleun J de Raaf et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(25), 3056-3060 (2013-07-31)
A 64-year-old woman with metastatic rectal cancer is admitted to the acute palliative care unit of our cancer center because of debilitating fatigue. She had been diagnosed with metastatic disease in 2009, when liver metastases were found 1 year after
Clinical practice. Attention deficit-hyperactivity disorder in children and adolescents.
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The New England journal of medicine, 370(9), 838-846 (2014-02-28)
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