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Merck
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Documenti fondamentali

M0506

Sigma-Aldrich

N-Methyl-DL-alanine

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About This Item

Formula empirica (notazione di Hill):
C4H9NO2
Numero CAS:
Peso molecolare:
103.12
Numero MDL:
Codice UNSPSC:
12352200
eCl@ss:
32160406
ID PubChem:

Saggio

≥98% (TLC)

Stato

powder

Colore

white

Stringa SMILE

CNC(C)C(O)=O

InChI

1S/C4H9NO2/c1-3(5-2)4(6)7/h3,5H,1-2H3,(H,6,7)
GDFAOVXKHJXLEI-UHFFFAOYSA-N

Azioni biochim/fisiol

N-Methyl-DL-alanine may be used in studies of amino acid transport mechanisms such as trans-stimulation. N-Methylalanine may be used in the construction of peptide and protein analogues for use in drug or antibiotic design and development.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Bang-zhi Zhang et al.
Peptides, 31(4), 568-573 (2010-01-05)
The actinomycin D (AMD) analogs in which the D-valine residues (the second amino acid residue in the cyclic depsipeptide of AMD) and the N-methyl-L-valine residues (the fifth amino acid residue in the cyclic depsipeptide of AMD) were replaced with D-Phe
G E Mann et al.
The Journal of physiology, 416, 485-502 (1989-09-01)
1. Epithelial uptake and efflux of the non-metabolized system A analogue 2-methylaminoisobutyric acid (MeAIB) and L-serine were studied in the isolated perfused rat pancreas using a dual tracer loading and wash-out technique. Uptakes of 2-[14C]MeAIB and L-[3H]serine were measured relative
Renata Perlikowska et al.
Basic & clinical pharmacology & toxicology, 106(2), 106-113 (2009-10-31)
A series of endomorphin-1 (EM-1) and endomorphin-2 (EM-2) analogues, containing non-cyclic amino acids (Ala, D-Ala, beta-Ala, NMeAla, D-NMeAla or Sar) instead of Pro in position 2 was synthesized, where NMeAla = N-methylalanine and Sar = N-methylglycine, sarcosine. The opioid activity
C H Tan et al.
Biochemical pharmacology, 39(5), 955-958 (1990-03-01)
Synaptosomes isolated from adult rat cerebral cortices were used for studying the uptake of L-leucine by the Na(+)-dependent route. Three non-metabolizable amino acid analogues, which had been used previously to discriminate the Na(+)-dependent A-type uptake system of animal cells, were
G Yadid et al.
Neuroscience, 55(4), 1147-1152 (1993-08-01)
[3H]Glycine is actively taken up into bovine isolated adrenal medulla chromaffin cells with the subsequent catecholamine release. [3H]Glycine uptake has two interaction sites based on relative Km measurements. These sites are inherently distinct since the effects of strychnine and temperature

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