L5647

Lidocaine hydrochloride monohydrate

≥99% (HPLC), solid, Na⁺ channel blocker

• Sinonimo/i: 2-Diethylamino-N-(2,6-dimethylphenyl)acetamide hydrochloride monohydrate, Lignocaine hydrochloride monohydrate, Xylocaine hydrochloride monohydrate
• Formula empirica (notazione di Hill): C₁₄H₂₂N₂O · HCl · H₂O
• Numero CAS: 6108-05-0
• Peso molecolare: 288.81
• Numero CE: 200-803-8
• Numero MDL: MFCD00150329
• Codice UNSPSC: 12352200
• ID PubChem: 24277718
• NACRES: NA.77

Proprietà

• product name: Lidocaine hydrochloride monohydrate, solid
• Forma fisica: solid
• Colore: white
• Solubilità: H₂O: soluble
• Stringa SMILE: Cl[H].[H]O[H].CCN(CC)CC(=O)Nc1c(C)cccc1C
• InChI: 1S/C14H22N2O.ClH.H2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H;1H2; YECIFGHRMFEPJK-UHFFFAOYSA-N
• Informazioni sul gene: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Descrizione

Descrizione generale

Lidocaine hydrochloride monohydrate is a commonly used as local anesthetic in topical applications and oral mucosal biopsies. It has a short anesthetic half-life.

Applicazioni

Lidocaine hydrochloride monohydrate has been used:

• in the preparation of drug composite for the controlled delivery in vitro, evaluated by drug release profile in ultra-high performance liquid chromatography (UPLC) and as a reference standard for fourier transform infrared spectroscopy (FT-IR).
• to record dose dependent response of sodium voltage (Nav1.7) channels in the injection-molded polymer device.
• For inhibition of glial cells in brain tissue samples.

Azioni biochim/fisiol

Na⁺ channel blocker; class IB antiarrhythmic that is rapidly absorbed after parenteral administration

Informazioni sulla sicurezza

• Pittogrammi: GHS06
• Avvertenze: Danger
• Indicazioni di pericolo: H301
• Consigli di prudenza: P301 + P310 + P330
• Classi di pericolo: Acute Tox. 3 Oral
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Faceshields, Gloves