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L5000

Sigma-Aldrich

N-Lauroylsarcosine, neat

≥95%

Sinonimo/i:

N-Dodecanoyl-N-methylglycine, Sarkosyl L

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About This Item

Formula condensata:
CH3(CH2)10CON(CH3)CH2COOH
Numero CAS:
97-78-9
Peso molecolare:
271.40
Numero CE:
202-608-3
Numero MDL:
MFCD00021749
Codice UNSPSC:
12161900
ID PubChem:
24896382
NACRES:
NA.21

Descrizione

anionic

Livello qualitativo

200

Saggio

≥95%

PM

average mol wt 600

Numero d'aggregazione

2

CMC

14.6

Stringa SMILE

CCCCCCCCCCCC(=O)N(C)CC(O)=O

InChI

1S/C15H29NO3/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19/h3-13H2,1-2H3,(H,18,19)
BACYUWVYYTXETD-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

N-Lauroylsarcosine is an anionic surfactant with an ability to denature proteins. Due to its microbicidal property, N-lauroylsarcosine is being considered as a potent anti-microbicide in topical formulations, especially against sexually transmitted diseases (STDs).

Stato fisico

May be liquid at room temperature

Pittogrammi

Skull and crossbonesCorrosion
GHS06,GHS05

Avvertenze

Danger

Indicazioni di pericolo

H315,H318,H330

Classi di pericolo

Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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N-lauroil-sarcosina European Pharmacopoeia (EP) Reference Standard

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N-lauroil-sarcosina

Sarcosine 98%

Sigma-Aldrich

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Dextran sulfate sodium salt from Leuconostoc spp. avg mol wt >500,000 (dextran starting material)

Sigma-Aldrich

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Dextran sulfate sodium salt from Leuconostoc spp.

Proteose-Peptone suitable for microbiology

Millipore

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Proteose-Peptone

Guanidina tiocianato for molecular biology, ≥99%

Sigma-Aldrich

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Guanidina tiocianato

Guanidina tiocianato ≥97% (titration)

Sigma-Aldrich

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Guanidina tiocianato

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Sigma-Aldrich

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Desossicolato di sodio

Reagente di bloccaggio For nucleic acid hybridization and detection

Roche

11096176001

Reagente di bloccaggio

Manganese(II) chloride solution BioReagent, for molecular biology, storage temp.:room temp

Sigma-Aldrich

M1787

Manganese(II) chloride solution

Roslyn N Brown et al.
Journal of proteome research, 9(9), 4454-4463 (2010-08-10)
A simple and effective subcellular proteomic method for fractionation based on osmotic lysis, differential centrifugation, and Sarkosyl solubilization was applied to the Gram-negative bacterium Shewanella oneidensis to gain insight into its subcellular architecture. Global differences in bacterial cytoplasm, inner membrane
Yoshiaki Furukawa et al.
The Journal of biological chemistry, 285(29), 22221-22231 (2010-04-21)
More than 100 different mutations in Cu,Zn-superoxide dismutase (SOD1) are linked to a familial form of amyotrophic lateral sclerosis (fALS). Pathogenic mutations facilitate fibrillar aggregation of SOD1, upon which significant structural changes of SOD1 have been assumed; in general, however
Kunie Ando et al.
The American journal of pathology, 178(2), 803-816 (2011-02-02)
Many models of human tauopathies have been generated in mice by expression of a human mutant tau with maintained expression of mouse endogenous tau. Because murine tau might interfere with the toxic effects of human mutant tau, we generated a
Jocelyne Piret et al.
Antimicrobial agents and chemotherapy, 46(9), 2933-2942 (2002-08-17)
The mechanisms of herpes simplex virus (HSV) inactivation by sodium lauryl sulfate (SLS) and n-lauroylsarcosine (LS), two anionic surfactants with protein denaturant potency, have been evaluated in cultured cells. Results showed that pretreatment of HSV type 1 (HSV-1) strain F
Yoshiaki Furukawa et al.
The Journal of biological chemistry, 286(21), 18664-18672 (2011-04-02)
The transactivation response element (TAR) DNA-binding protein-43 (TDP-43) is a nuclear protein that normally regulates transcription and splicing. Abnormal accumulation of insoluble inclusions containing TDP-43 has been recently reported in the affected tissues of amyotrophic lateral sclerosis (ALS) patients. Here
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