I117

R(+)-IAA-94

≥98% (HPLC), solid

• Sinonimo/i: Indanyloxyacetic acid 94, R(+)-Methylindazone, R(+)-[(6,7-Dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1H-inden-5-yl)-oxy]acetic acid
• Formula empirica (notazione di Hill): C₁₇H₁₈Cl₂O₄
• Numero CAS: 54197-31-8
• Peso molecolare: 357.23
• Codice UNSPSC: 12352200
• ID PubChem: 24277844
• NACRES: NA.77

Proprietà

• Saggio: ≥98% (HPLC)
• Stato: solid
• Attività ottica: [α]22/D +36.4°, c = 0.86 in methanol(lit.)
• Colore: white
• Solubilità: H₂O: 0.2 mg/mL; 0.1 M NaOH: 2.8 mg/mL; DMSO: >20 mg/mL; ethanol: 20 mg/mL; dilute aqueous acid: insoluble
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: C[C@@]1(Cc2cc(OCC(O)=O)c(Cl)c(Cl)c2C1=O)C3CCCC3
• InChI: 1S/C17H18Cl2O4/c1-17(10-4-2-3-5-10)7-9-6-11(23-8-12(20)21)14(18)15(19)13(9)16(17)22/h6,10H,2-5,7-8H2,1H3,(H,20,21)/t17-/m1/s1; RNOJGTHBMJBOSP-QGZVFWFLSA-N

Descrizione

Applicazioni

R(+)-IAA-94 has been used as a chloride ion channel inhibitor to study its effects on grepafloxacin uptake by human mononuclear (THP-1) cells . It has also been used as a chloride ion channel inhibitor to study its effects on moxifloxacin uptake by human mononuclear (THP-1) cells.

Caratteristiche e vantaggi

This compound is featured on the Chloride Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)