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G6019

Sigma-Aldrich

Glyceraldehyde-3-phosphate Dehydrogenase from human erythrocytes

lyophilized powder, 50-150 units/mg protein

Sinonimo/i:

D-Glyceraldehyde 3-phosphate:NAD+ oxidoreductase (phosphorylating), GAPDH

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About This Item

Numero CAS:
9001-50-7
Classificazione EC (Enzyme Commission):
1.2.1.12 (BRENDA, IUBMB)
Numero MDL:
MFCD00131203
Codice UNSPSC:
12352204
NACRES:
NA.54

Stato

lyophilized powder

Livello qualitativo

200

Attività specifica

50-150 units/mg protein

Composizione

Protein, 40-70% biuret

N° accesso UniProt

P04406

Attività estranea

3-Phosphoglyceric phosphokinase ≤2%

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... GAPDH(2597)

Azioni biochim/fisiol

Glyceraldehyde-3-phosphate dehydrogenase catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate as part of glycolysis. It has also been shown to have roles in initiation of apoptosis, transcription activation and the shuttling of ER to Golgi vesicles<<<18,New>>>.

Definizione di unità

One unit will reduce 1.0 μmole of 3-phosphoglycerate to D-glyceraldehyde 3-phosphate per min in a coupled system with 3-phosphoglyceric phosphokinase at pH 7.6 at 25 °C.

Stato fisico

Lyophilized powder containing sodium citrate buffer salts

Inibitore

N° Catalogo
Descrizione
Determinazione del prezzo

I2512

Sodium iodoacetate, ≥98%

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
SLCG9330
SLCF0006
061M7024
019K7540
018K75551

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Anti-GAPDH ~1&#160;mg/mL, affinity isolated antibody, buffered aqueous solution

Sigma-Aldrich

G9545

Anti-GAPDH

Monoclonal Anti-GAPDH clone GAPDH-71.1, purified from hybridoma cell culture

Sigma-Aldrich

G8795

Monoclonal Anti-GAPDH

Bing Fang et al.
Biochimie, 95(2), 251-257 (2012-09-27)
siRNA is promising in anti-tumor therapy. The main challenge is lack of tumor-specific intracellular delivery. In this study, a 6 amino acids peptide (A1) with high affinity for vascular endothelial growth factor receptor-1 (VEGFR1) was conjugated with a cell penetrating
Milan Jirků et al.
The Journal of eukaryotic microbiology, 59(6), 537-547 (2012-08-01)
Several new species of trypanosomatids (Euglenozoa, Kinetoplastea, Trypanosomatidae), isolated from the intestines of Neotropical insects (Heteroptera), were genotyped on the basis of spliced leader RNA, and also defined phylogenetically using gene sequences of small subunit ribosomal RNA and glycosomal glyceraldehyde
Pablo Moreno-Acosta et al.
Anticancer research, 32(10), 4319-4325 (2012-10-13)
The aim of this study was to evaluate the predictive utility of Insulin-like growth factor-1 receptor (IGF1R), IGF1, IGF2, Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and of hemoglobin levels for tumor response to exclusive radiotherapy, in patients with locally advanced Human papillomavirus
Kyle L Sunderland et al.
Journal of strength and conditioning research, 27(1), 1-7 (2012-10-23)
The purpose of this study was to investigate how age and 1 week of conventional resistance exercise affects commonly used housekeeping gene (HKG) messenger RNAs (mRNAs) in skeletal muscle. Ten college-aged (18-25 years) and 10 older (60-76 years) men completed
Shunqing Liang et al.
Veterinary immunology and immunopathology, 150(3-4), 198-205 (2012-10-23)
Edwardsiella tarda is a Gram-negative pathogen which causes systemic infection in turbot. The increasing frequency of edwardsiellosis in turbot farming has stressed the need to understand the immune responses of fish, for the further development of prevention and control strategies.
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