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Key Documents

F1506

Sigma-Aldrich

Sodium fumarate dibasic

≥99%

Sinonimo/i:

Disodium fumarate, Fumaric acid disodium salt

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About This Item

Formula condensata:
NaOOCCH=CHCOONa
Numero CAS:
Peso molecolare:
160.04
Beilstein:
4301302
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

Livello qualitativo

Saggio

≥99%

Stringa SMILE

[Na+].[Na+].[O-]C(=O)\C=C\C([O-])=O

InChI

1S/C4H4O4.2Na/c5-3(6)1-2-4(7)8;;/h1-2H,(H,5,6)(H,7,8);;/q;2*+1/p-2/b2-1+;;
MSJMDZAOKORVFC-SEPHDYHBSA-L

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Applicazioni

  • Enhancement of drug absorption: Sodium fumarate dibasic is utilized to improve the dissolution behavior and oral absorption of drugs with pH-dependent solubility, enhancing bioavailability and therapeutic efficacy in pharmaceutical applications (Salehi et al., 2021).
  • Development of novel drug carriers: The compound is used in the synthesis and characterization of novel injectable drug carriers, aiming to enhance the delivery and efficacy of therapeutic agents in medical treatment strategies (Guo et al., 2005).

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Acido citrico reagent grade, ≥98% (GC/titration)

Sigma-Aldrich

C7129

Acido citrico

Xueying Liu et al.
Molecules (Basel, Switzerland), 24(12) (2019-06-21)
The major objective of this study was to investigate the anti-chronic nonbacterial prostatitis (CNP) mechanism of T. patula by metabolomics and network pharmacology. The study demonstrated that the flavonoids and polysaccharides of T. patula could alleviate prostatitis by improving the
Wei Jin et al.
Current microbiology, 74(11), 1337-1342 (2017-08-02)
The effect of disodium fumarate (DF) on the ruminal fermentation profiles, the accumulation of lipopolysaccharide (LPS) and bioamines, and the composition of the ruminal bacterial community was investigated by in vitro rumen fermentation. The addition of DF increased the total
Miaomiao Jiang et al.
Scientific reports, 7(1), 8739-8739 (2017-08-20)
Metabonomics/metabolomics is a rapid technology for comprehensive profiling of small molecule metabolites in cells, tissues, or whole organisms, the application of which has led to understanding pathophysiologic mechanisms of cardiometabolic diseases, defining predictive biomarkers for those diseases, and also assessing
Yasemin D Yilmazel et al.
Bioelectrochemistry (Amsterdam, Netherlands), 119, 142-149 (2017-10-11)
Few microorganisms have been examined for current generation under thermophilic (40-65°C) or hyperthermophilic temperatures (≥80°C) in microbial electrochemical systems. Two iron-reducing archaea from the family Archaeoglobaceae, Ferroglobus placidus and Geoglobus ahangari, showed electro-active behavior leading to current generation at hyperthermophilic
Carl Roos et al.
Molecular pharmaceutics, 14(12), 4252-4261 (2017-09-19)
Currently, the screening of new drug candidates for intestinal permeation is typically based on in vitro models which give no information regarding regional differences along the gut. When evaluation of intestinal permeability by region is undertaken, two preclinical rat models

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