OAW42

85073102, human ovary, Epithelial

• Sinonimo/i: OAW-42 Cells
• Codice UNSPSC: 41106514

Proprietà

• product name: OAW42, 85073102
• Origine biologica: human ovary
• Modalità di accrescimento: Adherent
• Cariotipo: 2n = 86
• Morfologia: Epithelial
• Prodotti: Not specified
• Recettori: Not specified
• tecniche: cell culture | mammalian: suitable
• Malattie correlate: cancer
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −196°C

Descrizione

Origine della linea cellulare

Human ovarian tumour epithelial

Descrizione della linea cellulare

From an ascites of patient with ovarian cystadenocarcinoma. Has retained ability to form free floating cysts in vitro and produces extracellular matrix. Has defined chemosensitivity pattern. Valuable for studies on biology of human ovarian cancer.

Applicazioni

OAW42 has been used to investigate the cytotoxic potential of histone deacetylase 1 as a target for ovarian cancer immunotherapy and to study the effects of tazemetostat, a potent and selective EZH2 inhibitor, on OAW42 cell lines.

Profilo DNA

STR-PCR Data: Amelogenin: X
CSF1PO: 11
D13S317: 11
D16S539: 12,13
D5S818: 11,12
D7S820: 8
THO1: 6,7
TPOX: 8,11
vWA: 15,16

Terreno di coltura

DMEM + 2mM Glutamine + 1mM Sodium Pyruvate (NaP) + 20 IU/l Bovine Insulin + 10% Foetal Bovine Serum (FBS).

Mantenimento delle subcolture

Split sub-confluent cultures (70-80%) 1:3 to 1:6 i.e. seeding at 2-4x10,000 cells/cm² using 0.25% trypsin; 5% CO₂; 37°C.

Altre note

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