C9017
Concanavalin A from Canavalia ensiformis (Jack bean)
Sepharose™ conjugate, buffered aqueous suspension
Sinonimo/i:
ConA
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About This Item
Codice UNSPSC:
12161501
NACRES:
NA.32
Prodotti consigliati
Origine biologica
Canavalia ensiformis
Livello qualitativo
Coniugato
Sepharose™ conjugate
Forma fisica
buffered aqueous suspension
contiene
20% ethanol as preservative
Grado di funzionalizzazione
10-16 mg per mL
Matrice
Sepharose 4B
Attivazione matrice
cyanogen bromide
Gruppi immobilizzati alla matrice
amino
Braccio spaziatore
1 atom
Capacità
≥25 mg/mL binding capacity (thyroglobulin)
Temperatura di conservazione
2-8°C
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Applicazioni
Used for the purification of glycoproteins containing mannose.
Azioni biochim/fisiol
Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.
Stato fisico
Suspension in 0.1 M acetate buffer, pH 6.0, containing 1 M NaCl, and 1 mM each of CaCl2 , MgCl2, and MnCl2
Risultati analitici
Where reported, agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, containing Ca2+ and Mn2+ of a 1 mg per mL solution. This activity is the lowest concentration to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C.
Note legali
Sepharose is a trademark of Cytiva
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Avvertenze
Danger
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Repr. 2 - Resp. Sens. 1 - Skin Sens. 1
Codice della classe di stoccaggio
3 - Flammable liquids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
102.2 °F
Punto d’infiammabilità (°C)
39 °C
Certificati d'analisi (COA)
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