C7642
Concanavalin A from Canavalia ensiformis (Jack bean)
FITC conjugate, Type IV, lyophilized powder
Sinonimo/i:
ConA
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About This Item
Codice UNSPSC:
12352202
NACRES:
NA.32
Prodotti consigliati
Origine biologica
Canavalia ensiformis
Livello qualitativo
Coniugato
FITC conjugate
Tipo
Type IV
Stato
lyophilized powder
Composizione
Protein, 5-15% biuret
Grado di funzionalizzazione
3-6 mol FITC per mol protein
Impurezze
Carbohydrate, essentially free
Temperatura di conservazione
−20°C
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Applicazioni
For the fluorescent detection of glycoproteins containing α−D-mannose or α−D-glucose
Azioni biochim/fisiol
Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.
Confezionamento
Package size based on protein content
Stato fisico
Lyophilized powder containing phosphate buffer salts and NaCl
Risultati analitici
Where reported, agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, containing Ca2+ and Mn2+ of a 1 mg per mL solution. This activity is the lowest concentration to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Skin Sens. 1
Codice della classe di stoccaggio
13 - Non Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Dispositivi di protezione individuale
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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