C7505

L-Cystathionine

≥98% (TLC), suitable for UHPLC

• Sinonimo/i: (R)-S-(2-Amino-2-carboxyethyl)-L-homocysteine
• Formula empirica (notazione di Hill): C₇H₁₄N₂O₄S
• Numero CAS: 56-88-2
• Peso molecolare: 222.26
• Beilstein: 2505200
• Numero CE: 200-295-8
• Numero MDL: MFCD00036685
• Codice UNSPSC: 12352209
• ID PubChem: 24892965
• NACRES: NA.26

Proprietà

• Nome del prodotto: L-Cystathionine, ≥98% (TLC)
• Saggio: ≥98% (TLC)
• Stato: powder
• tecniche: UHPLC: suitable
• Colore: white
• Punto di fusione: >300 °C
• Temperatura di conservazione: −20°C
• Stringa SMILE: N[C@@H](CCSC[C@H](N)C(O)=O)C(O)=O
• InChI: 1S/C7H14N2O4S/c8-4(6(10)11)1-2-14-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)/t4-,5-/m0/s1; ILRYLPWNYFXEMH-WHFBIAKZSA-N

Descrizione

Applicazioni

L-Cystathionine has been used in ultra-performance liquid chromatography for the validation of cystathionine and the correlation of its abundance with vertebrate metamorphosis. It has also been used as an inhibitor of sinusoidal GSH (glutathione) carrier to signify that thiol redox state imbalance is associated with the modulation of autophagy in carcinoma cells.

Azioni biochim/fisiol

L-Cystathionine is an intermediate in the biosynthesis of L-cysteine and methionine. It is used as a substrate to differentiate and analyze cystathionine γ-lyase(s). L-Cystathionine is an important non-protein amino acid and is associated with metabolic disorders. In recent studies, L-cystathionine is believed to be the precursor of cyclic imino acid cyclothionine. Cystathioninuria is characterized with imino acid cyclothionine excretion in the urine.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)