H4628

DL-Homocysteine

≥95% (titration)

• Sinonimo/i: 2-Amino-4-mercaptobutyric acid
• Formula condensata: HSCH₂CH₂CH(NH₂)COOH
• Numero CAS: 454-29-5
• Peso molecolare: 135.18
• Beilstein: 1721683
• Numero CE: 207-222-9
• Numero MDL: MFCD00004898
• Codice UNSPSC: 12352209
• eCl@ss: 42021308
• ID PubChem: 24895646
• NACRES: NA.26

Proprietà

• product name: DL-Homocysteine, ≥95% (titration)
• Livello qualitativo: 200
• Saggio: ≥95% (titration)
• Forma fisica: powder
• Punto di fusione: 232-233 °C (lit.)
• Solubilità: H₂O: soluble
• applicazioni: cell analysis; peptide synthesis
• Temperatura di conservazione: −20°C
• Stringa SMILE: NC(CCS)C(O)=O
• InChI: 1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7); FFFHZYDWPBMWHY-UHFFFAOYSA-N

Descrizione

Applicazioni

DL-Homocysteine has been used to induce hyperhomocysteinemia in Sprague–Dawley rats. It has also been used to study the effects of hyperhomocysteinemia on atherosclerosis in apolipoprotein E-deficient mice.

Azioni biochim/fisiol

Homocysteine is a sulfhydryl-containing amino acid, synthesized from methionine. It is a non-essential, non-proteinogenic amino acid. It is an important determinant of the methylation cycle and is present in the plasma in four forms. An abnormally high level of homocysteine leads to hyperhomocysteinemia and also promotes atherosclerosis.

Increased plasma homocysteine is a risk factor for coronary heart disease and carcinogenesis; may be a marker for tumor cell growth.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)