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Key Documents

C5041

Sigma-Aldrich

6-Carboxyfluorescein diacetate

~95% purity (HPLC), powder

Sinonimo/i:

6-CFDA, 6-Carboxy-di-O-acetylfluorescein

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About This Item

Formula empirica (notazione di Hill):
C25H16O9
Numero CAS:
Peso molecolare:
460.39
Beilstein:
67043
Numero MDL:
Codice UNSPSC:
12171500
ID PubChem:
NACRES:
NA.47

product name

6-Carboxyfluorescein diacetate, ≥95% (HPLC)

Livello qualitativo

100
200

Saggio

≥95% (HPLC)

Forma fisica

powder

Colore

white to yellow

Solubilità

chloroform/ethanol (1:1): 9.80-10.20 mg/mL, clear, colorless to light yellow

applicazioni

diagnostic assay manufacturing
hematology
histology

Temperatura di conservazione

−20°C

Stringa SMILE

CC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C24OC(=O)c5ccc(cc45)C(O)=O)c1

InChI

1S/C25H16O9/c1-12(26)31-15-4-7-18-21(10-15)33-22-11-16(32-13(2)27)5-8-19(22)25(18)20-9-14(23(28)29)3-6-17(20)24(30)34-25/h3-11H,1-2H3,(H,28,29)
QMOGCCYGOPYYNT-UHFFFAOYSA-N

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Applicazioni

6-Carboxyfluorescein diacetate has been used to differentiate viable cells from apoptotic cells. Live cells that are not apoptotic accumulate 6-carboxyfluorescein but do not accumulate annexin.
Fluorescent wavelengths λex 492nm; λemm 517nm in 0.1M Tris, pH 8.0.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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International journal of pharmaceutics, 530(1-2), 113-127 (2017-07-26)
The aim of the present research is to increase lipid solubility, metabolic stability and therapeutic efficacy of water soluble gemcitabine (GEM) via phospholipid complex (PC) formation. A novel phospholipid complex of GEM was successfully prepared and optimized. Physical interaction of
Douglas E Brenneman et al.
Journal of molecular neuroscience : MN, 47(2), 368-379 (2012-04-27)
Severe seizure activity is associated with recurring cycles of excitotoxicity and oxidative stress that result in progressive neuronal damage and death. Intervention to halt these pathological processes is a compelling disease-modifying strategy for the treatment of seizure disorders. In the
G Ricci et al.
Human reproduction (Oxford, England), 17(10), 2665-2672 (2002-09-28)
Apoptosis plays an important role in regulating spermatogenesis. However, the biological significance of apoptosis in ejaculated sperm is not yet clear. This study set out to investigate how apoptosis correlates with semen quality and the presence of seminal leukocytes. Fifty-seven
Evaluation of sperm quality snakes Erythrolamprus poecilogyrus sublineatus (Cope, 1860) (Serpentes, Dipsadidae).
Silva AC, et al.
Brazilian journal of biology = Revista brasleira de biologia, doi: 10-doi: 10 (2017)
Garry R Smith et al.
Journal of molecular neuroscience : MN, 52(3), 446-458 (2013-11-28)
Severe seizure activity is associated with reoccurring cycles of excitotoxicity and oxidative stress that result in progressive neuronal damage and death. Intervention with these pathological processes is a compelling disease-modifying strategy for the treatment of seizure disorders. We have optimized

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