C4542

Cyclobenzaprine hydrochloride

• Sinonimo/i: 5-(3-Dimethylaminopropylidene)dibenzo[a,e]cycloheptatriene hydrochloride
• Formula empirica (notazione di Hill): C₂₀H₂₁N · HCl
• Numero CAS: 6202-23-9
• Peso molecolare: 311.85
• Numero CE: 228-264-4
• Numero MDL: MFCD00079039
• Codice UNSPSC: 12352200
• ID PubChem: 24278315
• NACRES: NA.77

Proprietà

• Stato: powder
• Livello qualitativo: 200
• Ideatore: Johnson & Johnson
• Stringa SMILE: Cl.CN(C)CC\C=C1\c2ccccc2C=Cc3ccccc13
• InChI: 1S/C20H21N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-14H,7,15H2,1-2H3;1H; VXEAYBOGHINOKW-UHFFFAOYSA-N
• Informazioni sul gene: human ... HTR2A(3356) , HTR2B(3357) , HTR2C(3358)

Descrizione

Descrizione generale

Cyclobenzaprine is a tricyclic agent, which has anti-depressant and anti-cholinergic properties. It lowers the tonic somatic motor activity of motor neuron systems. Cyclobenzaprine prevents the uptake of noradrenaline. It is used to treat neck, back and myofascial pain. Cyclobenzaprine functions as a nerve impulse inhibitor.

Applicazioni

Cyclobenzaprine hydrochloride has been used to study its effect on the muscles of dystrophin-deficient mdx5Cv mice.

Cyclobenzaprine hydrochloride has been used to study its effects on the muscles of dystrophin-deficient mdx5Cv mice.

Azioni biochim/fisiol

Cyclobenzaprine hydrochloride is a type of tricyclic skeletal drug, which is commonly used as a muscle relaxant. It is very effective in treating intractable pain of cervical and lumbar origin caused by skeletal muscle spasm. cyclobenzaprine hydrochloride inhibit tonic α-mononeuronal excitation mediated by descending serotonergic systems by interacting with serotonin receptors at the spinal cord level.

Skeletal muscle relaxant; reduces muscle spasm by depression of brainstem neurons; 5-HT₂ serotonin receptor antagonist.

Caratteristiche e vantaggi

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informazioni sulla sicurezza

• Pittogrammi: GHS06
• Avvertenze: Danger
• Indicazioni di pericolo: H301,H312 + H332
• Consigli di prudenza: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P312
• Classi di pericolo: Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Faceshields, Gloves