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C3355

Sigma-Aldrich

Coelenterazine hcp

≥95% (HPLC), solid

Sinonimo/i:

CLZN-hcp

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About This Item

Formula empirica (notazione di Hill):
C25H25N3O2
Numero CAS:
123437-32-1
Peso molecolare:
399.48
Numero MDL:
MFCD03453204
Codice UNSPSC:
12352204
ID PubChem:
24892609
NACRES:
NA.83

product name

Coelenterazine hcp, solid

Saggio

≥95% (HPLC)

Livello qualitativo

200

Forma fisica

solid

Solubilità

methanol: 1 mg/mL, clear, yellow to orange

Temperatura di conservazione

−20°C

Stringa SMILE

Oc1ccc(cc1)C2=CN3C(=O)C(Cc4ccccc4)=NC3=C(CC5CCCC5)N2

InChI

1S/C25H25N3O2/c29-20-12-10-19(11-13-20)23-16-28-24(21(26-23)14-17-8-4-5-9-17)27-22(25(28)30)15-18-6-2-1-3-7-18/h1-3,6-7,10-13,16-17,26,29H,4-5,8-9,14-15H2
YEGCUOQUFAXCMK-UHFFFAOYSA-N

Descrizione generale

Coelenterazine hcp is a semisynthetic analog of coelenterazine.

Applicazioni

Coelenterazine hcp has been used:
  • as a component of coelenterazine reagent in the reporter assay
  • in the purification of Renilla luciferase-labeled Annexin V
  • in evaluating the activity of aequorin in Escherichia coli

Azioni biochim/fisiol

Coelenterazine hcp has 190 times higher luminescence intensity than native coelenterazine and a faster response time than native coelenterazine.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Yao Cheng et al.
Plant & cell physiology, 59(5), 978-988 (2018-02-13)
Seed germination is sensitive to salt stress. ABA and Ca2+ are involved in the regulation of seed germination under salt stress. Ca2+ influx mediated by glutamate receptors (GLRs) plays important roles in many physiological processes in plants. Here, we investigated
Mahboobeh Nazari et al.
The Analyst, 137(21), 5062-5070 (2012-09-25)
The Ca(2+)-dependent binding of Annexin V to phosphatidylserine on cell surfaces is a reliable marker for apoptosis that is widely used in flow cytometry based apoptosis assays. In this paper, we report a new class of Annexin V-based probes for
Sarah E Webb et al.
Molecular reproduction and development, 82(7-8), 563-586 (2014-01-03)
In this review, we take a retrospective look at the discovery and utilization of the Ca(2+) -sensitive bioluminescent protein complex, aequorin. We do consider the contribution it has made to our understanding of the natural phenomenon of bioluminescence, but it
Mehdi Zeinoddini et al.
Photochemistry and photobiology, 86(5), 1071-1075 (2010-07-29)
An aequorin-based Escherichia coli strain JM109 biosensor was constructed and characterized for its potential to detect toluene and related compounds in aqueous solutions. The biosensor was constructed based on a PGL2 plasmid carrying the lower pathway promoter (Pu) of the
Klaus Eyer et al.
Scientific reports, 5, 16551-16551 (2015-11-21)
The unwanted emergence of neutralizing antibodies (nAbs) against an endogenous or a therapeutic protein can result in deficiency diseases or therapy failure. Here, we developed a cell-free microfluidic method for the sensitive detection and quantification of nAbs in human serum

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