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Key Documents

C1629

Sigma-Aldrich

Choline bitartrate

Sinonimo/i:

2-(Hydroxyethyl)trimethylammonium bitartrate

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About This Item

Formula empirica (notazione di Hill):
C9H19NO7
Numero CAS:
Peso molecolare:
253.25
Numero CE:
Codice UNSPSC:
12352200
ID PubChem:
NACRES:
NA.77

Forma fisica

powder

Stringa SMILE

[O-]C([C@H](O)[C@@H](O)C(O)=O)=O.C[N+](C)(C)CCO

InChI

1S/C5H14NO.C4H6O6/c1-6(2,3)4-5-7;5-1(3(7)8)2(6)4(9)10/h7H,4-5H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/q+1;/p-1/t;1-,2-/m.1/s1
QWJSAWXRUVVRLH-LREBCSMRSA-M

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Applicazioni

Choline bitartrate has been used as one of the components in experimental diets to study the effects on reproductive processes and on bone genes during gestation and lactation.

Azioni biochim/fisiol

Choline bitartrate is known to serve as a dietary supplement. Choline acts as a precursor for acetylcholine synthesis.
Acyl group acceptor

Substrati

Choline acetyltransferase substrate

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


Certificati d'analisi (COA)

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SAFC

PHG0021

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Lard oil

Sigma-Aldrich

L0657

Lard oil

Extra virgin olive oil in maternal diet increases osteogenic genes expression, but high amounts have deleterious effects on bones in mice offspring at adolescence
Mousavi SN, et al.
Iranian Journal of Basic Medical Sciences, 19(12), 1299-1299 (2016)
Yumna Zia et al.
The Journal of nutrition, 148(10), 1513-1520 (2018-10-04)
Phosphatidylethanolamine N-methyltransferase (PEMT) converts phosphatidylethanolamine to phosphatidylcholine. Pemt-/-/low density lipoprotein receptor (Ldlr)-/- mice have significantly reduced plasma lipids and are protected against atherosclerosis. Recent studies have shown that choline can be metabolized by the gut flora into trimethylamine-N-oxide (TMAO), which
No acute effects of choline bitartrate food supplements on memory in healthy, young, human adults
Lippelt DP, et al.
PLoS ONE, 11(6), e0157714-e0157714 (2016)
Effects of Diets Enriched in Omega-9 or Omega-6 Fatty Acids on Reproductive Process
Mousavi SN, et al.
Journal of family & reproductive health, 10(2), 85-85 (2016)
Paulina Aldana-Hernández et al.
The Journal of nutritional biochemistry, 92, 108617-108617 (2021-03-12)
Choline is an essential nutrient required for various biological processes. Eggs, dairy, and meat are rich in phosphatidylcholine (PC), whereas cereal and legumes are rich in free choline. Excess dietary choline leads to increase plasma trimethylamine N-oxide (TMAO). Epidemiological studies

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