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Key Documents

A6559

Sigma-Aldrich

Adenosine 5′-triphosphate disodium salt solution

Crystalline ATP, HPLC purified, aqueous solution for RNA transcription

Sinonimo/i:

ATP

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About This Item

Numero CAS:
Numero MDL:
Codice UNSPSC:
41106305
eCl@ss:
32160414
ID PubChem:
NACRES:
NA.52

Livello qualitativo

Forma fisica

liquid

Concentrazione

100 mM in H2O (adjusted to pH 7 with Trizma®
base)

Attività estranea

DNase, RNase, none detected

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O

InChI

1S/C10H16N5O13P3.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
TTWYZDPBDWHJOR-IDIVVRGQSA-L

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Descrizione generale

Adenosine 5′-triphosphate disodium salt solution is suitable for use in molecular biology applications such as kinase reactions or DNA-dependent RNA polymerase transcription.

Applicazioni

Adenosine 5′-triphosphate disodium salt solution has been used:
  • as a standard to evaluate the extracellular ATP release from marginal cells of stria vascular
  • as a component of the internal pipette solution to establish a recording electrode to study neurite stretching
  • in in vitro VPS34 (catalytic subunit of the phosphatidylinositol 3-kinase (PtdIns3K) complex) activity assay
  • as a component of lysis and resealing buffers for ATP studies
  • in spectrophotometric measurement of H+ transport in fluorescein isothiocyanate (FITC)-dextran loaded A549 (adenocarcinomic human alveolar basal epithelial cells) and HeLa cells
  • to induce pyroptosis in lipopolysaccharide treated fibroblast-like synoviocytes (FLSs)

Azioni biochim/fisiol

Adenosine 5′-triphosphate (ATP) is an important energy currency in all living organisms. It possesses high phosphate transfer potential. ATP is involved in several biological processes such as membrane transport, muscle contraction and synthesis, and degradation of biological molecules. It plays a role as an intracellular and extracellular signaling molecule in certain cellular processes such as cell motility, organ development, neurotransmission, and insulin secretion.

Note legali

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Certificati d'analisi (COA)

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