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A5282

Sigma-Aldrich

DL-2-Amino-5-phosphonopentanoic acid

≥98% (TLC), solid, NMDA receptor antagonist

Sinonimo/i:

5-Phosphono-DL-norvaline, DL-2-Amino-5-phosphonovaleric acid, AP-5, APV

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About This Item

Formula empirica (notazione di Hill):
C5H12NO5P
Numero CAS:
76326-31-3
Peso molecolare:
197.13
Beilstein:
2446389
Numero MDL:
MFCD00010515
Codice UNSPSC:
12352106
ID PubChem:
24277950
NACRES:
NA.32

product name

DL-2-Amino-5-phosphonopentanoic acid, solid

Forma fisica

solid

Colore

white

Solubilità

0.1 M NaOH: 4 mg/mL
H2O: 5.6 mg/mL
organic solvents: insoluble

Stringa SMILE

NC(CCCP(O)(O)=O)C(O)=O

InChI

1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)
VOROEQBFPPIACJ-UHFFFAOYSA-N

Informazioni sul gene

rat ... Grik1(29559) , Grin2a(24409) , Grin2b(24410)

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Applicazioni

DL-2-Amino-5-phosphonopentanoic acid has been used:
  • in the inactivation of N-methyl-D-aspartate (NMDA)-mediated synapses
  • used in growth medium for inhibition of electrical activity in the neuronal network
  • used to isolate N-methyl-D-aspartate receptors (NMDAR) or α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR)-mediated currents were isolated using this product
  • used in double distilled water to compare its NMDA antagonistic action with that of prion protein (PrPC)

Azioni biochim/fisiol

Anticonvulsant; potent and selective NMDA receptor antagonist.

Avvertenza

Hygroscopic

Altre note

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Biomedical Microdevices, 11(2), 495-501 (2009)
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