Passa al contenuto
Merck
Tutte le immagini(1)

Key Documents

Altri documenti

A1910

Sigma-Aldrich

(±)-2-Amino-4-phosphonobutyric acid

solid

Sinonimo/i:

(±)-AP-4

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(1)

About This Item

Formula empirica (notazione di Hill):
C4H10NO5P
Numero CAS:
20263-07-4
Peso molecolare:
183.10
Numero MDL:
MFCD00013999
ID PubChem:
57653830
NACRES:
NA.32

Forma fisica

solid

Colore

white

Stringa SMILE

NC(CCP(O)(O)=O)C(O)=O

InChI

1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)
DDOQBQRIEWHWBT-UHFFFAOYSA-N

Informazioni sul gene

human ... GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRINA(2907)
rat ... Grin2b(24410)

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

(±)-2-Amino-4-phosphonobutyric acid or DL-AP4 is a group III nonselective metabotropic glutamate receptor (mGluR) agonist. L-2-amino-4-phosphonobutyric acid (L-Ap4) displays close to 500-fold selectivity for group III mGluRs.

Applicazioni

(±)-2-Amino-4-phosphonobutyric acid may be used as a glutamic acid receptor blocker in perfusion solution in the eye tissue electroretinography studies.

Azioni biochim/fisiol

NMDA glutamate receptor antagonist.

Avvertenza

Hygroscopic, store desiccated.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 5

1 of 5

98%

Sigma-Aldrich

268615

3-Aminopropylphosphonic acid

DNQX ≥98% (TLC)

Sigma-Aldrich

D0540

DNQX

NMDA receptor antagonist

Sigma-Aldrich

A8054

D(−)-2-Amino-5-phosphonopentanoic acid

99%

Sigma-Aldrich

268674

2-Aminoethylphosphonic acid

powder

Sigma-Aldrich

M107

(+)-MK-801 hydrogen maleate

H-M Zhang et al.
Neuroscience, 158(2), 875-884 (2008-11-20)
Chronic neuropathic pain remains an unmet clinical problem because it is often resistant to conventional analgesics. Metabotropic glutamate receptors (mGluRs) are involved in nociceptive processing at the spinal level, but their functions in neuropathic pain are not fully known. In
Haruhisa Okawa et al.
Nature communications, 10(1), 2167-2167 (2019-05-17)
Ribbon synapses transmit information in sensory systems, but their development is not well understood. To test the hypothesis that ribbon assembly stabilizes nascent synapses, we performed simultaneous time-lapse imaging of fluorescently-tagged ribbons in retinal cone bipolar cells (BCs) and postsynaptic
Satoshi Okado et al.
Investigative ophthalmology & visual science, 58(12), 5518-5525 (2017-10-28)
We determined the effects of a remodeled inner retina on the flicker electroretinograms (ERGs) in a rabbit eye at an advanced stage of inherited retinal degeneration. Six wild-type (WT) and four rhodopsin P347L transgenic (Tg) rabbits were studied at 18
Jared D Chrispell et al.
Investigative ophthalmology & visual science, 59(12), 5116-5124 (2018-10-30)
To define the functional roles of Grk1 and Grk7 in zebrafish cones in vivo. Genome editing was used to generate grk7a and grk1b knockout zebrafish. Electroretinogram (ERG) analyses of the isolated cone mass receptor potential and the b-wave were performed
Nicolás M Díaz et al.
Investigative ophthalmology & visual science, 61(6), 37-37 (2020-06-17)
Autonomous molecular circadian clocks are present in the majority of mammalian tissues. These clocks are synchronized to phases appropriate for their physiologic role by internal systemic cues, external environmental cues, or both. The circadian clocks of the in vivo mouse
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.