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A1910

Sigma-Aldrich

(±)-2-Amino-4-phosphonobutyric acid

solid

Sinonimo/i:

(±)-AP-4

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About This Item

Formula empirica (notazione di Hill):
C4H10NO5P
Numero CAS:
20263-07-4
Peso molecolare:
183.10
Numero MDL:
MFCD00013999
Codice UNSPSC:
12352106
ID PubChem:
57653830
NACRES:
NA.32

Forma fisica

solid

Colore

white

Stringa SMILE

NC(CCP(O)(O)=O)C(O)=O

InChI

1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)
DDOQBQRIEWHWBT-UHFFFAOYSA-N

Informazioni sul gene

human ... GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRINA(2907)
rat ... Grin2b(24410)

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Descrizione generale

(±)-2-Amino-4-phosphonobutyric acid or DL-AP4 is a group III nonselective metabotropic glutamate receptor (mGluR) agonist. L-2-amino-4-phosphonobutyric acid (L-Ap4) displays close to 500-fold selectivity for group III mGluRs.

Applicazioni

(±)-2-Amino-4-phosphonobutyric acid may be used as a glutamic acid receptor blocker in perfusion solution in the eye tissue electroretinography studies.

Azioni biochim/fisiol

NMDA glutamate receptor antagonist.

Avvertenza

Hygroscopic, store desiccated.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

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