A2093

Aspirin

meets USP testing specifications

• Sinonimo/i: Acetylsalicylic acid, 2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin
• Formula condensata: 2-(CH₃CO₂)C₆H₄CO₂H
• Numero CAS: 50-78-2
• Peso molecolare: 180.16
• Beilstein: 779271
• Numero CE: 200-064-1
• Numero MDL: MFCD00002430
• Codice UNSPSC: 12352106
• ID PubChem: 24890623
• NACRES: NA.21

Proprietà

• agenzia: USP/NF; meets USP testing specifications
• Livello qualitativo: 200
• Forma fisica: powder or crystals
• Punto di fusione: 134-136 °C (lit.)
• applicazioni: pharmaceutical (small molecule)
• Stringa SMILE: CC(=O)Oc1ccccc1C(O)=O
• InChI: 1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12); BSYNRYMUTXBXSQ-UHFFFAOYSA-N
• Informazioni sul gene: human ... ITGA2B(3674) , PTGS1(5742) , PTGS2(5743)

Descrizione

Descrizione generale

Aspirin (acetylsalicylic acid) is a nonsteroidal anti-inflammatory drug. It occurs as white crystalline powder and is derived from salicylic acid.

Applicazioni

Aspirin has been used:

• as a stabilizer for blood during 13,14-dihydro-15-keto-prostaglandin F2α (PGFM) measurement
• to evaluate cell viability of BV-2 microglial cell line
• in morphogenesis assay

Azioni biochim/fisiol

Aspirin is an analgesic and antipyretic agent used in the treatment of fever and pain as in arthritis. It is also associated with cardiovascular diseases.

Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302
• Consigli di prudenza: P264 - P270 - P301 + P312 - P501
• Classi di pericolo: Acute Tox. 4 Oral
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 482.0 °F
• Punto d’infiammabilità (°C): 250 °C
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Faceshields, Gloves