17793

Quercetin 3-β-D-glucoside

≥90% (HPLC)

• Sinonimo/i: 3,3′,4′,5,7-Pentahydroxyflavone 3-β-glucoside, Isoquercitrin
• Formula empirica (notazione di Hill): C₂₁H₂₀O₁₂
• Numero CAS: 482-35-9
• Peso molecolare: 464.38
• Beilstein: 100989
• Numero MDL: MFCD00017746
• Codice UNSPSC: 12352205
• ID PubChem: 57647673
• NACRES: NA.25

Proprietà

• Saggio: ≥90% (HPLC)
• applicazioni: metabolomics; vitamins, nutraceuticals, and natural products
• Temperatura di conservazione: −20°C
• Stringa SMILE: OC[C@H]1O[C@@H](OC2=C(Oc3cc(O)cc(O)c3C2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15-,17+,18-,21+/m1/s1; OVSQVDMCBVZWGM-QSOFNFLRSA-N
• Informazioni sul gene: mouse ... Hexa(15211)

Descrizione

Descrizione generale

Quercetin 3-β-D-glucoside (Q3G), also known as isoquercitrin, is one of the major glycosidic forms of quercetin. It is a mono-glucoside, first isolated from the seed pods of Cercis canadensis L., it is also found in various plants, vegetables, and fruits. Q3G has the basic chemical structure of a flavonoid, with a glucose molecule attached to the C-3 of quercetin.

Applicazioni

Quercetin 3-β-D-glucoside has been used:

• as a dietary flavonoid supplement to check its binding capacity with human small ubiquitin-related modifier 1 (SUMO1) protein using surface plasmon resonance (SPR)
• as an inhibitor for Escherichia coli adenosine triphosphate (ATP) synthase
• as an anti-aggregation agent to test its activity against β-amyloid, green fluorescent protein (GFP), and chymotrypsinogen proteins

Azioni biochim/fisiol

Quercetin 3-β-D-glucoside possesses strong antioxidant and anti-inflammatory activities. Being a potent oxygen-radical scavenger, it is a neuroprotective agent that improves Alzheimer′s disease (AD) condition in mice models. It has shown antiproliferative activity against colon, lung, and hepatocellular cell lines and MCF-7 human breast cancer cells in combination with apple extracts.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)