496189

Cloroformio

biotech. grade, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

• Sinonimo/i: Triclorometano, Tricloruro di metilidina
• Formula empirica (notazione di Hill): CHCl₃
• Numero CAS: 67-66-3
• Peso molecolare: 119.38
• Beilstein: 1731042
• Numero MDL: MFCD00000826
• Codice UNSPSC: 12191502
• ID PubChem: 329757487
• NACRES: NA.04
• Grado: biotech. grade
• Saggio: ≥99.8%
• P. ebollizione: 60.5-61.5 °C (lit.)
• Tensione di vapore: 160 mmHg ( 20 °C)

Proprietà

• Grado: biotech. grade
• Livello qualitativo: 100
• Densità del vapore: 4.1 (vs air)
• Tensione di vapore: 160 mmHg ( 20 °C)
• Saggio: ≥99.8%
• Stato: liquid
• contiene: 0.5-1.0% ethanol as stabilizer
• Impurezze: <0.01% water
• Residuo dopo evaporazione: <0.0003%
• Colore: APHA: ≤10
• Indice di rifrazione: n20/D 1.445 (lit.)
• pH: 5.2-6.4
• P. ebollizione: 60.5-61.5 °C (lit.)
• Punto di fusione: −63 °C (lit.)
• Densità: 1.48 g/mL at 25 °C; 1.492 g/mL at 25 °C (lit.)
• Cationi in tracce: Pb: ≤0.05 ppm
• Stringa SMILE: ClC(Cl)Cl
• InChI: 1S/CHCl3/c2-1(3)4/h1H; HEDRZPFGACZZDS-UHFFFAOYSA-N

Descrizione

Descrizione generale

Chloroform is a colorless, volatile chlorinated organic solvent whose vapors have a narcotic effect. It is susceptible to degradation with time, which can be suppressed by adding ethanol as a stabilizer. Since ethanol is added in higher concentration it leads to increase in polarity which may have a potential influence on some of the applications. Low water content, minimal residue and clean UV spectra are the special characteristics of this biotech grade solvent. It can be utilized for biotechnological processes like protein sequencing, peptide and oligonucleotide synthesis. Reports suggest that chloroform stabilized with ethanol reduces chances on creating artifacts during the chromatographic separation after extraction of anthracyclines from biological matrices.

Applicazioni

Chloroform may be used in the following processes:

• Synthesis of colloidal hydrophobic CdSe core nanocrystals (quantum dots).
• Preparing phospholipid solutions.
• As a solvent in the photolysis reaction of ruthenium complexes.
• Solvent for recrystallization.
• Reference compound to detect the presence of chloroform in Tobacco smokes.
• Extractant in solvent extraction process.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H315,H319,H331,H336,H351,H361d,H372
• Consigli di prudenza: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Classi di pericolo: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Organi bersaglio: Central nervous system, Liver,Kidney
• Codice della classe di stoccaggio: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): does not flash
• Punto d’infiammabilità (°C): does not flash