16201

Tannic acid

puriss., powder

• Sinonimo/i: Gallotannin, Tannin
• Formula empirica (notazione di Hill): C₇₆H₅₂O₄₆
• Numero CAS: 1401-55-4
• Peso molecolare: 1701.20
• Beilstein: 8186396
• Numero CE: 215-753-2
• Numero MDL: MFCD00066397
• Codice UNSPSC: 12352106
• ID PubChem: 329751144
• NACRES: NA.21

Proprietà

• Grado: puriss.
• Livello qualitativo: 200
• Stato: powder
• Temp. autoaccensione: 980 °F
• Qualità: meets analytical specification of USP
• Impurezze: dextrines, gum matters, in accordance; resinous matters, in accordance
• Residuo alla calcinazione: ≤0.1% (as SO₄)
• Perdita: ≤9% loss on drying, 105 °C, 2 h
• Punto di fusione: 218 °C (lit.)
• Solubilità: H₂O: soluble 1 gm in 0.35ml; glycerol: soluble 1gm in 1 ml (warm); acetone: very soluble; alcohol: freely soluble (Diluted); alcohol: slightly soluble (Dehydrated); alcohol: very soluble; benzene: insoluble; carbon disulfide: insoluble; carbon tetrachloride: insoluble; chloroform: insoluble; diethyl ether: insoluble; hexane: insoluble; petroleum ether: insoluble
• applicazioni: metabolomics; vitamins, nutraceuticals, and natural products
• Stringa SMILE: Oc1cc(cc(O)c1O)C(=O)Oc2cc(cc(O)c2O)C(=O)OC[C@H]3O[C@@H](OC(=O)c4cc(O)c(O)c(OC(=O)c5cc(O)c(O)c(O)c5)c4)[C@H](OC(=O)c6cc(O)c(O)c(OC(=O)c7cc(O)c(O)c(O)c7)c6)[C@@H](OC(=O)c8cc(O)c(O)c(OC(=O)c9cc(O)c(O)c(O)c9)c8)[C@@H]3OC(=O)c%10cc(O)c(O)c(OC(=O)c%11cc(O)c(O)c(O)c%11)c%10
• InChI: 1S/C76H52O46/c77-32-1-22(2-33(78)53(32)92)67(103)113-47-16-27(11-42(87)58(47)97)66(102)112-21-52-63(119-72(108)28-12-43(88)59(98)48(17-28)114-68(104)23-3-34(79)54(93)35(80)4-23)64(120-73(109)29-13-44(89)60(99)49(18-29)115-69(105)24-5-36(81)55(94)37(82)6-24)65(121-74(110)30-14-45(90)61(100)50(19-30)116-70(106)25-7-38(83)56(95)39(84)8-25)76(118-52)122-75(111)31-15-46(91)62(101)51(20-31)117-71(107)26-9-40(85)57(96)41(86)10-26/h1-20,52,63-65,76-101H,21H2/t52-,63-,64+,65-,76+/m1/s1; LRBQNJMCXXYXIU-PPKXGCFTSA-N

Descrizione

Descrizione generale

Tannic acid is the simplest hydrolyzable tannin. The chemical structure of tannic acid has a glucose molecule in its core connected to 10 galloyls groups via aliphatic ester bonds. TA is one of the most abundant natural polyphenols, which can be colorless to yellow in color, and of astringent taste. It can be sourced from the bark of oak, chestnut, hemlock, mangrove, etc.

Applicazioni

Tannic acid has been used:

• as a reference standard to measure the total hydrolyzable tannins in Oak root bark tannin-methanol extract using a UV/Vis spectrophotometer
• as a blood-brain barrier (BBB) impermeable, transcytosis-inhibiting drug in spheroid culture medium
• as a flushing agent to test its effects on metal ions, total organic carbon, and organic matter of soil
• as an inhibitor of free ovalbumin (OVA) uptake by the endocytic mechanism on dendritic cells

Azioni biochim/fisiol

Tannic acid has many pharmacological properties such as antioxidant, anti-inflammatory, antimicrobial, and anti-tumor effects. It also exerts anti-aging, wound healing, and neuroprotective activities. TA is traditionally used as a tanning agent in the food, leather, adhesive, and pharmaceutical industries. It is a natural crosslinker that is useful in building polymeric networks and can be used to design biomedical hydrogels.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): 390.2 °F
• Punto d’infiammabilità (°C): 199 °C