PHR1582

Dehydroacetic acid

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinonimo/i: Dehydroacetic acid, 2-Acetyl-5-hydroxy-3-oxo-4-hexenoic acid δ-lactone
• Formula empirica (notazione di Hill): C₈H₈O₄
• Numero CAS: 520-45-6
• Peso molecolare: 168.15
• Beilstein: 6129
• Numero CE: 208-293-9
• Numero MDL: MFCD00066709
• Codice UNSPSC: 41116107
• ID PubChem: 329823490
• NACRES: NA.24

Proprietà

• Grado: certified reference material; pharmaceutical secondary standard
• Livello qualitativo: 300
• agenzia: traceable to USP 1166309
• Famiglia di API: dehydroacetic acid
• CdA: current certificate can be downloaded
• Confezionamento: pkg of 1 g
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• P. eboll.: 270 °C (lit.)
• Punto di fusione: 111-113 °C (lit.)
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Temperatura di conservazione: 2-30°C
• Stringa SMILE: CC(=O)C1C(=O)OC(C)=CC1=O
• InChI: 1S/C8H8O4/c1-4-3-6(10)7(5(2)9)8(11)12-4/h3,7H,1-2H3; PGRHXDWITVMQBC-UHFFFAOYSA-N

Descrizione

Descrizione generale

Dehydroacetic acid is a pyrone derivative, that is typically synthesized by the base-catalyzed dimerization of diketene. It is used as a preservative in pharmaceutical, food and cosmetic products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Applicazioni

Dehydroacetic acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical, food and cosmetic formulations by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAA4498 in the slot below. This is an example certificate only and may not be the lot that you receive.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302
• Consigli di prudenza: P264 - P270 - P301 + P312 - P501
• Classi di pericolo: Acute Tox. 4 Oral
• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 314.6 °F
• Punto d’infiammabilità (°C): 157 °C