PHR1331
Metformin Related Compound A
Pharmaceutical Secondary Standard; Certified Reference Material
Sinonimo/i:
Dicyandiamide, Cyanoguanidine, Dicyanodiamide
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About This Item
Formula condensata:
NH2C(=NH)NHCN
Numero CAS:
Peso molecolare:
84.08
Beilstein:
605637
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24
Prodotti consigliati
Grado
certified reference material
pharmaceutical secondary standard
Livello qualitativo
agenzia
traceable to USP 1396310
Famiglia di API
metformin
CdA
current certificate can be downloaded
tecniche
HPLC: suitable
gas chromatography (GC): suitable
Punto di fusione
208-211 °C (lit.)
applicazioni
pharmaceutical (small molecule)
Formato
neat
Temperatura di conservazione
2-8°C
Stringa SMILE
NC(=N)NC#N
InChI
1S/C2H4N4/c3-1-6-2(4)5/h(H4,4,5,6)
QGBSISYHAICWAH-UHFFFAOYSA-N
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Descrizione generale
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
It is an impurity of the widely used antidiabetic drug, metformin, that belongs to the biguanide class of compounds.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
It is an impurity of the widely used antidiabetic drug, metformin, that belongs to the biguanide class of compounds.
Applicazioni
This pharmaceutical secondary standard can also be used as follows:
- Separation and estimation of metformin along with other antidiabetics from meglitinides class in the presence of metformin impurity cyanoguanidine using a liquid chromatography method in pharmaceutical formulations
- Development of a reversed phase-high performance liquid chromatographic (RP-HPLC) method combined with a UV-diode array detector (PDA) for the impurity analysis of combined dosage tablet of metformin hydrochloride and teneligliptin hydrobromide hydrate
- Estimation of empagliflozin, linagliptin, along with metformin and its related impurities cyanoguanidine and melamine using HPLC-DAD and high-performance thin layer chromatography (HPTLC) methods in their combined tablets
- Development and validation of a stability indicating capillary zone electrophoresis (CZE) method for the quantification of metformin and its major impurity in pharmaceutical formulation
- Simultaneous determination of vildagliptin, metformin, and metformin-related compounds (A, B, and C) in tablets using a high-performance liquid chromatography-tandem mass spectrometry method (HPLC-MS/MS)
Risultati analitici
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Nota a piè di pagina
To see an example of a Certificate of Analysis for this material enter LRAA0834 in the slot below. This is an example certificate only and may not be the lot that you receive.
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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Certificati d'analisi (COA)
Lot/Batch Number
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