PHR1253

Acarbose

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinonimo/i: 4",6"-Dideoxy-4"-([1S]-[1,4,6/5]-4,5,6-trihydroxy-3-hydroxymethyl-2-yclohexenylamino)-maltotriose
• Formula empirica (notazione di Hill): C₂₅H₄₃NO₁₈
• Numero CAS: 56180-94-0
• Peso molecolare: 645.60
• Numero CE: 260-030-7
• Numero MDL: MFCD00869592
• Codice UNSPSC: 41116107
• ID PubChem: 329823256
• NACRES: NA.24

Proprietà

• Grado: certified reference material; pharmaceutical secondary standard
• Livello qualitativo: 300
• agenzia: traceable to Ph. Eur. Y0000500; traceable to USP 1000521
• Famiglia di API: acarbose
• CdA: current certificate can be downloaded
• Classi chimiche degli analiti: oligosaccharides
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• applicazioni: food and beverages; pharmaceutical (small molecule)
• Formato: neat
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: C[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O[C@@H]2CO)O[C@H]3[C@H](O)[C@@H](O)[C@H](O)O[C@@H]3CO)[C@H](O)[C@@H](O)[C@@H]1N[C@H]4C=C(CO)[C@@H](O)[C@H](O)[C@H]4O
• InChI: 1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1; XUFXOAAUWZOOIT-SXARVLRPSA-N
• Informazioni sul gene: human ... AMY2A(279) , MGAM(8972)

Descrizione

Descrizione generale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Acarbose is an oral antidiabetic drug, a glucosidase inhibitor used in the management of non-insulin-dependent diabetes mellitus (NIDDM).

Applicazioni

Acarbose may be used as a pharmaceutical reference standard in determining the concentration of the analyte in pharmaceutical formulations by chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Azioni biochim/fisiol

Modified tetrasaccharide that acts as a reversible α -glucosidase inhibitor.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAA9057 in the slot below. This is an example certificate only and may not be the lot that you receive.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1