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Documenti fondamentali

PHR1176

Supelco

Tryptophan

Pharmaceutical Secondary Standard; Certified Reference Material

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About This Item

Numero CAS:
Numero CE:
Codice UNSPSC:
41116107
eCl@ss:
32160406
NACRES:
NA.24

Grado

certified reference material
pharmaceutical secondary standard

Livello qualitativo

agenzia

traceable to Ph. Eur. T2610000
traceable to USP 1700501

Famiglia di API

tryptophan

CdA

current certificate can be downloaded

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-30°C

Stringa SMILE

[nH]1c2c(c(c1)CC(N)C(=O)O)cccc2

InChI

1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)
QIVBCDIJIAJPQS-UHFFFAOYSA-N

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Descrizione generale

Tryptophan is an essential amino acid and a precursor for the synthesis of serotonin (5-HT), a neuromodulator responsible for modulating sleep and appetite regulation.

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.

Applicazioni

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Tryptophan may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometric techniques.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Values of analytes vary lot to lot.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAB2382 in the slot below. This is an example certificate only and may not be the lot that you receive.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Applicazioni

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

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The use of carbon paste electrode in the direct voltammetric determination of tryptophan in pharmaceutical formulations
Fiorucci AR, et al.
Journal of Pharmaceutical and Biomedical Analysis, 28(5), 909-915 (2002)
Evolution of tryptophan and its foremost metabolites? concentrations in milk and fermented dairy products
Bertazzo A, et al.
PharmaNutrition, 4(2), 62-67 (2016)
Differential spectrophotometric determination of tyrosine and tryptophan in pharmaceutical amino acid solutions
Demeester J, et al.
Journal of Pharmaceutical Sciences, 67(5), 729-730 (1978)
Tryptophan supplementation modulates social behavior: a review
Steenbergen L, et al.
Neuroscience and Biobehavioral Reviews, 64, 346-358 (2016)
Heedeok Hong et al.
Biochemistry, 52(25), 4413-4421 (2013-06-15)
Lipid solvation provides the primary driving force for the insertion and folding of integral membrane proteins. Although the structure of the lipid bilayer is often simplified as a central hydrophobic core sandwiched between two hydrophilic interfacial regions, the complexity of

Protocolli

Separation of L-Alanine; Glycine; L-Valine; L-Leucine; L-Isoleucine; L-Proline; L-Methionine; L-Serine; L-Threonine; L-Phenylalanine; L-Aspartic acid; L-4-Hydroxyproline; L-Cysteine; L-Glutamic acid; L-Asparagine; L-Lysine; L-Glutamine; L-Histidine; L-Tyrosine; L-Tryptophan; L-Cystine

Chromatograms

application for HPLC

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