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Key Documents

PHR1000

Supelco

D-(+)-Glucosio

Pharmaceutical Secondary Standard; Certified Reference Material

Sinonimo/i:

Destrosio

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About This Item

Formula empirica (notazione di Hill):
C6H12O6
Numero CAS:
Peso molecolare:
180.16
Beilstein:
1724615
Numero CE:
Numero MDL:
Codice UNSPSC:
12352201
ID PubChem:
NACRES:
NA.24

Grado

certified reference material
pharmaceutical secondary standard

Livello qualitativo

agenzia

traceable to Ph. Eur. Y0001745
traceable to USP 1181302

Famiglia di API

dextrose

Saggio

99.9%

CdA

current certificate can be downloaded

Classi chimiche degli analiti

oligosaccharides

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

detection
food and beverages
pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-30°C

Stringa SMILE

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
WQZGKKKJIJFFOK-DVKNGEFBSA-N

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Descrizione generale

Dextrose belongs to the class of sugars, and is a preferred source of carbohydrate in parenteral nutrition regimens. It is widely used in solutions to adjust tonicity, as a sweetening agent, wet granulation diluent/binder, direct-compression tablet diluent/binder, etc. It is considered only for short term clinical use, since it is deficient in electrolytes.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Applicazioni

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Dextrose has been used as a standard in the determination of additives like glucose in beverages using high performance liquid chromatography (HPLC). It may also be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric technique.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAB7785 in the slot below. This is an example certificate only and may not be the lot that you receive.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

Lot/Batch Number

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Supelco

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Sigma-Aldrich

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Maltotriosio Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

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Sigma-Aldrich

D9559

D--(+)-Glucosio

A multicommuted flow system for the determination of dextrose in parenteral and hemodialysis concentrate solutions
Knochen M, et al. et al.
Journal of Pharmaceutical and Biomedical Analysis, 37(4), 823-828 (2005)
Determination of Additives in Beverages Using Ascentis Express Columns
Shimelis O, et al.
Sigma data, 30 (2013)
Handbook of Pharmaceutical Excipients (1986)
Saunders Handbook of Veterinary Drugs - E-Book: Small and Large Animal (2010)
Handbook of Starch Hydrolysis Products and their Derivatives (1995)

Protocolli

RP-Amide and HILIC, both amenable to the analysis of polar compounds, were successfully used to resolve several beverage components, including sugars, vitamins, sweeteners, preservatives, and caffeine.

HPLC Analysis of Sugars on SUPELCOSIL™ LC-NH2

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