M4627
1-Methylnicotinamide chloride
analytical standard
Sinonimo/i:
N-Methylnicotinic acid amide chloride
Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
About This Item
Formula condensata:
C7H9N2OCl
Numero CAS:
Peso molecolare:
172.61
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24
Prodotti consigliati
Grado
analytical standard
Livello qualitativo
Saggio
≥97.5%
Stato
powder
tecniche
HPLC: suitable
gas chromatography (GC): suitable
Colore
white
applicazioni
forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products
Formato
neat
Stringa SMILE
[Cl-].C[n+]1cccc(c1)C(N)=O
InChI
1S/C7H8N2O.ClH/c1-9-4-2-3-6(5-9)7(8)10;/h2-5H,1H3,(H-,8,10);1H
BWVDQVQUNNBTLK-UHFFFAOYSA-N
Descrizione generale
1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced mainly by nicotinamide N-methyltransferase (NNMT) and exhibits antithrombotic and anti-inflammatory effects.
Applicazioni
1-Methylnicotinamide chloride may be used as a standard in the quantification of 1-methylnicotinamide in urine samples using ion pairing reverse-phase high performance liquid chromatography (RP-HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Azioni biochim/fisiol
Urinary excretion product of niacin metabolism
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
Scegli una delle versioni più recenti:
Possiedi già questo prodotto?
I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
I clienti hanno visto anche
Stefan Chłopicki et al.
Pharmacological reports : PR, 64(2), 369-376 (2012-06-05)
Methylnicotinamide (MNA) displays vasoprotective activity, however, the regulation of the activity of nicotinamide-N-methyltransferase (NNMT), is largely unknown. We analyze a possible involvement of IL-6 in the activation of NNMT-MNA pathway during an endurance exercise. FVB, C57Bl/6J IL6(+/+) and C57Bl/6J IL-6(-/-)
Magdalena Sternak et al.
Pharmacological reports : PR, 62(3), 483-493 (2010-07-16)
Nicotinamide N-methyltransferase (NNMT), which converts nicotinamide (NA) to 1-methylnicotinamide (MNA), is up-regulated in the cirrhotic liver. Because MNA displays PGI(2)-dependent anti-inflammatory effects, the up-regulation of NNMT may play a regulatory role in liver inflammation. In the present work, we analyzed
Misha Patel et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 921-922, 87-95 (2013-02-26)
Nicotinamide N-methyltransferase (NNMT, E.C. 2.1.1.1) N-methylates nicotinamide to produce 1-methylnicotinamide. Enhanced NNMT activity is a feature of many types of cancer, and has been linked to processes such as tumour metastasis, resistance to radiotherapy and tumour drug resistance. As such
Tamara Kuchmerovska et al.
Neurochemistry international, 56(2), 221-228 (2009-10-20)
The present study has been designed to establish the potential benefits from 1-methylnicotinamide (MNA) treatment on brain disorders associated with type 1 diabetes. All experiments were carried out after 6 weeks of streptozotocin-induced diabetes (60 mg/kg of body weight, i.p.)
Wu-Ping Sun et al.
Hypertension research : official journal of the Japanese Society of Hypertension, 35(2), 180-185 (2011-09-16)
Nicotinamide and catecholamines are both degraded by S-adenosylmethionine-dependent methylation. Whether excess nicotinamide affects the degradation of catecholamines is unknown. The aim of this study was to investigate the effect of nicotinamide on the methylation status of the body and methylation-mediated
Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
Contatta l'Assistenza Tecnica.