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M2649

Sigma-Aldrich

Melanin from Sepia officinalis

99% purity (TLC), powder

Sinonimo/i:

Melanin

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About This Item

Numero CAS:
8049-97-6
Numero CE:
232-473-6
Numero MDL:
MFCD00131581
Codice UNSPSC:
12171500
NACRES:
NA.47

product name

Melanin from Sepia officinalis, 99% (TLC)

Livello qualitativo

200

Saggio

99% (TLC)

Forma fisica

powder

Solubilità

hydrogen peroxide: 1 mg/mL, dark brown

applicazioni

diagnostic assay manufacturing
hematology
histology

Temperatura di conservazione

−20°C

InChI

1S/C18H10N2O4/c1-5-13-9-7(3-19-13)12-10-8(11(9)17(23)15(5)21)4-20-14(10)6(2)16(22)18(12)24/h3-4,19-20H,1-2H3
XUMBMVFBXHLACL-UHFFFAOYSA-N

Categorie correlate

Descrizione generale

Melanin is a ubiquitous and prominent pigment responsible for color of skin, hair and eyes. Melanin is classified into eumelanin and pheomelanin. Eumelanin is black to dark brown pigment and is present in black hair and retina of the eye. Pheomelanin is yellow to reddish brown pigment present is red hair and red feathers. Melanins are high molecular weight pigments synthesized from phenolic or indolic precursors and is widely present in animals, plants and microorganisms.

Applicazioni

Melanin from Sepia officinalis has been used:
  • as a natural pigment for Raman spectroscopy measurements
  • in competitive enzyme linked immunosorbent assay (ELISA) for the characterization of phage antibodies
  • as an external standard for spectrophotometrically determining the melanin production in B16F10 cells

Azioni biochim/fisiol

Melanin scavenges active chemical species and acts as a sunscreen.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
103H1023
100H0118
099F0746

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Optical properties of melanin in the skin and skinlike phantoms.
Bashkatov AN
SPIE Proc. (2000)
Sunil Kalia et al.
Pigment cell & melanoma research, 31(1), 31-38 (2017-08-15)
Objective measurements of melanin can provide important information for differentiating melanoma from benign pigmented lesions and in assessing pigmentary diseases. Herein, we evaluate near-infrared (NIR) fluorescence as a possible tool to quantify melanin. Various concentrations of in vitro Sepia melanin
Bor-Kai Hsiung et al.
The Journal of experimental biology, 218(Pt 22), 3632-3635 (2015-10-10)
Melanin pigments are broadly distributed in nature - from bacteria to fungi to plants and animals. However, many previous attempts to identify melanins in spiders were unsuccessful, suggesting that these otherwise ubiquitous pigments were lost during spider evolution. Yet, spiders
Detection of antibodies against Paracoccidioides brasiliensis melanin in in vitro and in vivo studies during infection.
Uran ME
Clinical and Vaccine Immunology : CVI, 18, 1680-1680 (2011)
Influence of rosmarinic acid and Salvia officinalis extracts on melanogenesis of B16F10 cells
Oliveira KB, et al.
Revista Brasileira de Farmacognosia, 23(2), 249-258 (2013)
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