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F0048010

Fenofibrate impurity B

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic acid, Fenofibric acid

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About This Item

Formula empirica (notazione di Hill):
C17H15ClO4
Numero CAS:
42017-89-0
Peso molecolare:
318.75
Beilstein:
2058973
Numero MDL:
MFCD00792461
Codice UNSPSC:
41116107
ID PubChem:
329799626
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

fenofibrate

Produttore/marchio commerciale

EDQM

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

O=C(C1=CC=C(OC(C)(C)C(O)=O)C=C1)C2=CC=C(Cl)C=C2

InChI

1S/C17H15ClO4/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11/h3-10H,1-2H3,(H,20,21)
MQOBSOSZFYZQOK-UHFFFAOYSA-N

Informazioni sul gene

human ... PPARA(5465)

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Fenofibrate impurity B EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

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Pittogrammi

Exclamation markEnvironment
GHS07,GHS09

Avvertenze

Warning

Indicazioni di pericolo

H302,H410

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

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Certificati d'analisi (COA)

Lot/Batch Number

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S Pourbaix et al.
Biochemical pharmacology, 33(22), 3661-3666 (1984-11-15)
Hamsters were given a diet containing fenofibrate (0.5% or 0.05%) or its metabolite, LF 2151 (0.15% or 0.015%) or a standard diet for a 3-week period. At the end of this period, the analysis of plasma lipids showed that the
Rapid determination of procetofenic acid in plasma by high-performance liquid chromatography.
M C Caturla et al.
Journal of chromatography, 227(1), 219-222 (1982-01-08)
R Aldini et al.
British journal of pharmacology, 74(3), 611-617 (1981-11-01)
1 Hypolipidaemic agents may increase biliary cholesterol in man, inducing a supersaturated bile. 2 To evaluate this possible side-effect, we have studied bile lipid secretion over a period of 8 h with intact enterohepatic circulation and 4 h with complete
Simple and rapid method for determining procetofenic acid, an active metabolite of procetofen, in biological fluids by solid-phase extraction and high-performance liquid chromatography.
A C Ramusino et al.
Journal of chromatography, 383(2), 419-424 (1986-12-19)
Inactivation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in cultured human blood mononuclear cells by procetofenic acid.
C Massaroli et al.
Pharmacological research communications, 14(1), 51-60 (1982-01-01)
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