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B0600000

Benzocaine

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

4-Aminobenzoic acid ethyl ester, Ethyl 4-aminobenzoate

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About This Item

Formula empirica (notazione di Hill):
C9H11NO2
Numero CAS:
94-09-7
Peso molecolare:
165.19
Beilstein:
638434
Numero MDL:
MFCD00007892
Codice UNSPSC:
41116107
ID PubChem:
329773120
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

benzocaine

Produttore/marchio commerciale

EDQM

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

CCOC(=O)c1ccc(N)cc1

InChI

1S/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3
BLFLLBZGZJTVJG-UHFFFAOYSA-N

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Benzocaine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H317

Classi di pericolo

Skin Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

233.6 °F

Punto d’infiammabilità (°C)

112 °C

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L A Linares et al.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 18(3), 267-269 (1990-07-01)
Methemoglobinemia is a condition in which more than 2% of the hemoglobin of the blood has been oxidized to the ferric form, a molecule which is incapable of binding oxygen or carbon dioxide. Clinically, the patient appears lethargic, cyanotic, and
Methemoglobinemia: a complication after fiberoptic orotracheal intubation with benzocaine spray. A case report.
F D Ellis et al.
The Journal of bone and joint surgery. American volume, 77(6), 937-939 (1995-06-01)
H A Cooper
Southern medical journal, 90(9), 946-948 (1997-09-26)
Acute methemoglobinemia is a medical emergency that can rapidly become fatal. A substantial number of drugs, including topical preparations, can precipitate this condition. I report a rare example of severe, acute methemoglobinemia caused by oropharyngeal anesthesia with topical benzocaine spray
Ahmed Dahshan et al.
Pediatrics, 117(4), e806-e809 (2006-04-06)
Severe methemoglobinemia resulting from the use of topical benzocaine has been reported in adults as a rare complication. Here we report a case of severe acquired methemoglobinemia resulting from topical use of benzocaine spray during diagnostic upper gastrointestinal endoscopy in
Daniel D Moos et al.
Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates, 30(5), 342-345 (2007-12-01)
Benzocaine administration to facilitate upper endoscopic procedures can result in the relatively uncommon but potentially fatal complication known as methemoglobinemia. For this reason, the Veterans Health Administration (VA) announced on February 8, 2006, that they would stop using benzocaine-containing sprays
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