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91209

Supelco

Carnosic acid

analytical standard

Sinonimo/i:

(4aR,10aS)-5,6-Dihydroxy-7-isopropyl-1,1-dimethyl-1,3,4,9,10,10a-hexahydro-2H-phenanthrene-4a-carboxylic acid, Salvin

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About This Item

Formula empirica (notazione di Hill):
C20H28O4
Numero CAS:
Peso molecolare:
332.43
Beilstein:
2707918
Numero MDL:
Codice UNSPSC:
85151701
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Saggio

≥95.0% (HPLC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Impurezze

≤5.0% water

applicazioni

food and beverages

Formato

neat

Temperatura di conservazione

−20°C

Stringa SMILE

CC(C)c1cc2CC[C@H]3C(C)(C)CCC[C@]3(C(O)=O)c2c(O)c1O

InChI

1S/C20H28O4/c1-11(2)13-10-12-6-7-14-19(3,4)8-5-9-20(14,18(23)24)15(12)17(22)16(13)21/h10-11,14,21-22H,5-9H2,1-4H3,(H,23,24)/t14-,20+/m0/s1
QRYRORQUOLYVBU-VBKZILBWSA-N

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Descrizione generale

Carnosic acid is a polyphenolic diterpene, which can be obtained from rosemary. It may possess various pharmacological properties like antioxidant, anticancer and also antimutagenic property.

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

Lot/Batch Number

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Carnosic acid inhibits proliferation and augments differentiation of human leukemic cells induced by 1, 25-dihydroxyvitamin dsub3 and retinoic acid
Steiner M, et al.
Nutrition and Cancer, 41, 135-144 (2001)
Michael Danilenko et al.
Experimental cell research, 298(2), 339-358 (2004-07-22)
Differentiation therapy holds promise as an alternative to cytotoxic drug therapy of cancer. Among compounds under scrutiny for this purpose is the physiologically active form of vitamin D(3), 1,25-dihydroxyvitamin D(3), and its chemically modified derivatives. However, the propensity of vitamin
Margarita González-Vallinas et al.
PloS one, 9(6), e98556-e98556 (2014-06-04)
Colorectal and pancreatic cancers remain important contributors to cancer mortality burden and, therefore, new therapeutic approaches are urgently needed. Rosemary (Rosmarinus officinalis L.) extracts and its components have been reported as natural potent antiproliferative agents against cancer cells. However, to
María Romo-Vaquero et al.
PloS one, 9(4), e94687-e94687 (2014-04-16)
Carnosic acid (CA) and rosemary extracts (RE) show body-weight, energy metabolism and inflammation regulatory properties in animal models but the mechanisms are not yet understood. Gut microbiota plays an important role in the host metabolism and inflammatory status and is
Leila Maringer et al.
Electrophoresis, 36(2), 348-354 (2014-10-14)
The combination of CE and MS is now a widely used tool that can provide a combination of high resolution separations with detailed structural information. Recently, we highlighted the benefits of an approach to add further functionality to this well-established

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