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Key Documents

74593

Supelco

Obidoxime chloride

analytical standard

Sinonimo/i:

1,1′-(Oxydimethylene)bis(pyridinium-4-carbaldoxime) dichloride, Bis(4-formylpyridiniomethyl) ether dioxime, Toxogonin

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About This Item

Formula empirica (notazione di Hill):
C14H16Cl2N4O3
Numero CAS:
Peso molecolare:
359.21
Beilstein:
4117377
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Saggio

≥97.0% (HPLC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Impurezze

≤1.0% water (calculated from elemental analysis)

Formato

neat

Stringa SMILE

[Cl-].[Cl-].O\N=C\c1cc[n+](COC[n+]2ccc(cc2)\C=N\O)cc1

InChI

1S/C14H14N4O3.2ClH/c19-15-9-13-1-5-17(6-2-13)11-21-12-18-7-3-14(4-8-18)10-16-20;;/h1-10H,11-12H2;2*1H
ZIFJVJZWVSPZLE-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

Obidoxime chloride is a drug, belonging to the group of oximes. It is found to be useful for the treatment of organophosphorus (OP) poisoning, since it has the ability to reverse the binding of organophosphorus compounds to the enzyme acetylcholinesterase (AChE).

Applicazioni

Obidoxime chloride may be used as a reference standard for the determination of obidoxime in a parenteral injection device using high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

Antidote for organophosphate nerve agent poisoning

Prodotti consigliati

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Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

Lot/Batch Number

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Simple high-performance liquid chromatographic method for determination of atropine and obidoxime in a parenteral injection device.
Journal of Chromatography A, 1057(1-2), 237-239 (2004)
Handbook of Toxicology of Chemical Warfare Agents (2015)
Best Synthetic Methods: Organophosphorus (V) Chemistry (2014)
Handbook of Pesticide Toxicology, Two-Volume Set: Principles and Agents, Volume 1, 1(2) (2001)
Dietrich E Lorke et al.
Journal of applied toxicology : JAT, 39(11), 1506-1515 (2019-07-03)
Organophosphates, useful agents as pesticides, also represent a serious danger due to their high acute toxicity. There is indication that oximes, when administered before organophosphate exposure, can protect from these toxic effects. We have tested at equitoxic dosage (25% of

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