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230987

Sigma-Aldrich

Victoria Pure Blue BO

Dye content 90 %

Sinonimo/i:

Basic Blue 7

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About This Item

Formula empirica (notazione di Hill):
C33H40ClN3
Numero CAS:
2390-60-5
Peso molecolare:
514.14
Colour Index:
42595
Numero CE:
219-232-0
Numero MDL:
MFCD00011877
Codice UNSPSC:
12171500
ID PubChem:
24853845
NACRES:
NA.47

Stato

powder, crystals or chunks

Livello qualitativo

100

Composizione

Dye content, 90%

Solubilità

95% ethanol: 0.1%, blue to very deep blue

λmax

619 nm

applicazioni

diagnostic assay manufacturing
hematology
histology

Temperatura di conservazione

room temp

Stringa SMILE

[Cl-].CCNc1ccc(\C(c2ccc(cc2)N(CC)CC)=C3/C=C\C(C=C3)=[N+](\CC)CC)c4ccccc14

InChI

1S/C33H39N3.ClH/c1-6-34-32-24-23-31(29-13-11-12-14-30(29)32)33(25-15-19-27(20-16-25)35(7-2)8-3)26-17-21-28(22-18-26)36(9-4)10-5;/h11-24H,6-10H2,1-5H3;1H
ROVRRJSRRSGUOL-UHFFFAOYSA-N

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Descrizione generale

Victoria blue dyes are triaminodiphenylnaphthylmethanes, with lipophilic cations and large conjugated systems.

Avvertenze

Danger

Indicazioni di pericolo

H301,H318,H410

Classi di pericolo

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
SHBM2410
MKCH0861
MKBK5906V
MKBL8015V
MKBK1928V

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Sigma-Aldrich

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Sigma-Aldrich

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M Wainwright et al.
Journal of chemotherapy (Florence, Italy), 11(1), 61-68 (1999-03-17)
The toxicities and phototoxicities of methylene blue (MB), toluidine blue O (TBO) and Victoria blue BO (VBBO) in a murine mammary tumour cell line (EMT6-S) and a multidrug resistant (MDR) sub-line (EMT6-R) were measured and their efficacy against the resistant
J Morgan et al.
Photochemistry and photobiology, 71(6), 747-757 (2000-06-17)
The relative contribution, to cell death, of photodynamic damage to respiratory proteins (known targets of photodynamic therapy with many photosensitizers) and other cellular sites was examined. The models were a human ovarian carcinoma cell line 2008, and its mitochondrial DNA-deficient
J Morgan et al.
Photochemistry and photobiology, 67(1), 155-164 (1998-04-04)
The cationic photosensitizing triaryl methane dye Victoria Blue BO (VBBO) localizes in mitochondria and causes oxidative damage to this organelle during photodynamic therapy (PDT). Oxidative stresses from other photosensitizers induce a variety of stress proteins. The endoplasmic reticulum (ER)-based, calcium-binding
S M Burrow et al.
Membrane & cell biology, 14(3), 357-366 (2001-05-23)
Victoria Blue BO (VBBO) is thought to exert its photocytotoxic effects via free radical generation. Glutathione and related enzymes are associated with the protection of normal tissues against free-radical damage and have also been implicated in multiple drug resistance. It
M Fiedorowicz et al.
Photochemistry and photobiology, 58(3), 356-361 (1993-09-01)
Photodynamic induced cytotoxicity by Victoria blue BO (VB-BO), merocyanine 540 (MC540), Nile blue A (NB) and 4-tetrasulfonatophenyl-porphyrin (4-TSPP) has been studied on two human leukemic cell lines: K-562 and TF-1. Cells were incubated with dyes and irradiated with different doses
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