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201316

Sigma-Aldrich

Quinaldine Red

Dye content 95 %

Sinonimo/i:

2-(4-Dimethylaminostyryl)-1-ethylquinolinium iodide

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About This Item

Formula empirica (notazione di Hill):
C21H23IN2
Numero CAS:
117-92-0
Peso molecolare:
430.33
Beilstein:
3798055
Numero CE:
204-221-5
Numero MDL:
MFCD00011968
Codice UNSPSC:
12171500
ID PubChem:
24852005
NACRES:
NA.47

Forma fisica

powder or crystals

Livello qualitativo

200

Composizione

Dye content, 95%

tecniche

titration: suitable

Solubilità

ethanol: 1 mg/mL, clear, dark red

λmax

528 nm

applicazioni

diagnostic assay manufacturing
hematology
histology

Temperatura di conservazione

room temp

Stringa SMILE

[I-].CC[n+]1c(\C=C\c2ccc(cc2)N(C)C)ccc3ccccc13

InChI

1S/C21H23N2.HI/c1-4-23-20(16-12-18-7-5-6-8-21(18)23)15-11-17-9-13-19(14-10-17)22(2)3;/h5-16H,4H2,1-3H3;1H/q+1;/p-1
JOLANDVPGMEGLK-UHFFFAOYSA-M

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Categorie correlate

Applicazioni

Quinaldine Red has been used as a fluorescent probe for α1-acid glycoprotein (AAG).

Azioni biochim/fisiol

Quinaldine Red (2-(p-Dimethylaminostyryl) quinoline ethiodide) is a very dark red or reddish-black colored powder. It has been used mainly for regulation of cell proliferation, in diagnostic agents of disease related with amyloid accumulation, detecting enzyme activity and dental bleaching materials. In addition, quinaldine red also been implicated in treatment of allodynia and virus infectious diseases. It is colorless at pH 1.4 and red at pH 3.2.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
MKCK2556
MKCC9357
MKBV5617V
MKBS8022V
MKBL5652

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World Health Organization
The International Pharmacopoeia, 1 (2006)
H Imamura et al.
Pharmaceutical research, 11(4), 566-570 (1994-04-01)
We examined different fluorescent probes suitable for fluorometric determination of alpha 1-acid glycoprotein (AGP) in serum. Quinaldine red (QR) was shown to bind strongly and selectively to AGP. Taking advantage of the enhanced fluorescence of QR in the presence of
H Imamura et al.
Biological & pharmaceutical bulletin, 16(9), 926-929 (1993-09-01)
We attempted to develop a fluorescent probe superior to conventional ones (8-anilino-1-naphthalenesulfonate and auramine O) for use in the study of drug-binding sites on alpha 1-acid glycoprotein (AGP). It was found that quinaldine red (QR) strongly bound to AGP and
A I Ivanov et al.
Clinical and experimental medicine, 2(3), 147-155 (2002-11-26)
The acute-phase response alters the composition of carrier proteins in plasma, which may affect the blood deposition and transport of biomediators and drugs. The effect of the acute-phase response on the ligand binding ability of plasma was studied in leukemic
Paul Zuck et al.
Analytical biochemistry, 342(2), 254-259 (2005-06-14)
Miniaturization of high-throughput screening (HTS) assays has several obvious advantages, including increased throughput and lower cost by reduction in reagent consumption. Although absorbance assays are widely used in research laboratories, their application for HTS in a low-volume format has been
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