14400

Biotina

≥99.0% (T)

• Sinonimo/i: Biotina-D, Bios II, Coenzima R, Vitamina B7, Vitamina H
• Formula empirica (notazione di Hill): C₁₀H₁₆N₂O₃S
• Numero CAS: 58-85-5
• Peso molecolare: 244.31
• Beilstein: 86838
• Numero CE: 200-399-3
• Numero MDL: MFCD00005541
• Codice UNSPSC: 12352201
• eCl@ss: 34058011
• ID PubChem: 329750287
• NACRES: NA.21

Proprietà

• Origine biologica: synthetic
• Livello qualitativo: 200
• Saggio: ≥99.0% (T)
• Forma fisica: powder
• Attività ottica: [α]20/D +91±2°, c = 1% in 0.1 M NaOH
• Residuo alla calcinazione: ≤0.1% (as SO₄)
• Perdita: ≤0.5% loss on drying
• Colore: colorless to white
• Punto di fusione: 229-234 °C; 231-233 °C (lit.)
• Solubilità: alcohol: soluble 80mg/100 ml at 25 °C; water: soluble 22mg/100 ml at 25 °C; 0.1 M NaOH: 10 mg/mL at 25 °C, clear, colorless; H₂O: very soluble; organic solvents: insoluble
• Cationi in tracce: Ca: ≤50 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤10 mg/kg; K: ≤50 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤500 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• applicazioni: detection
• Stringa SMILE: [H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2
• InChI: 1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1; YBJHBAHKTGYVGT-ZKWXMUAHSA-N

Descrizione

Descrizione generale

Biotin is readily available in several foods, like whole grains, nuts, legumes, unpolished rice and egg yolk. The normal gut flora also produces this vitamin.

Applicazioni

Biotin has been used for testing the functionality of the Avidin-displaying phages. The product has also been used for labeling the swine anti-rabbit IgG antibody and peroxidase.

Azioni biochim/fisiol

Biotin acts as an important cofactor for carboxylase enzymes in various metabolic pathways. Biotin favors keratin synthesis and hence is used as a supplement for hair and nail growth. Deficiency of biotin shows several symptoms such as alopecia, conjunctivitis, seborrheic dermatitis, depression, lethargy, hypotonia and seizures.

Biotin also referred to as vitamin H or vitamin B7 is a water-soluble B-vitamin that induces two to three fold increase in guanylate cyclase activity in rat liver, kidney, colon, cerebellum, and heart. It also stimulates the sperm motility and prolongs the survival of cryopreserved human spermatozoa.

Altre note

Reviews; Avidin-Biotin technology;

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)