MABT84

Anti-Aggrecan Antibody, clone 1-C-6

clone 1-C-6, from mouse

• Sinonimo/i: Aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPCP
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: 1-C-6, monoclonal
• Reattività contro le specie: mouse, rat, bovine
• tecniche: immunohistochemistry: suitable; western blot: suitable
• Isotipo: IgG1κ
• N° accesso NCBI: NP_071526
• N° accesso UniProt: P07897
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... ACAN(176)

Descrizione

Descrizione generale

Aggregating chondroitin sulfate proteoglycan or aggrecan, is one of the most studied proteoglycans. Many individual monomers of aggrecan bind to hyaluronic acid to form an aggregate, the monomer is known as aggrecan. The aggregates are comprised of up to 100 monomers attached to a single chain of hyaluronic acid. The high content of negatively charged polysaccharide chains contributes to the osmotic swelling of cartilage and in combination with intact collagen fibers results in articular cartilage resistance to compressive forces and high tensile strength. Aggrecan is abundant in articular cartilage and compromises 10% of its dry weight.

Immunogeno

Reduced and alkylated Aggrecan isolated from Swarm Rat Chondrosarcoma

Applicazioni

This Anti-Aggrecan Antibody, clone 1-C-6 is validated for use in IH, WB for the detection of Aggrecan.

Western Blot Analysis: 1 µg/mL from a representative lot detected Aggrecan on 10 µg of A1D4 protein fraction from Bovine tissue.

Qualità

Evaluated by Immunohistochemistry in normal mouse cartilage and normal rat cartilage tissues.

Immunohistochemistry Analysis: A 1:1,000 dilution of this antibody detected Aggrecan in normal mouse cartilage and normal rat cartilage tissues.

Descrizione del bersaglio

Various

Stato fisico

Format: Purified

Risultati analitici

Control
Normal mouse cartilage and normal rat cartilage tissues

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable