MABT37

Anti-Dentin sialoprotein Antibody, clone 2C12.3

clone 2C12.3, from mouse

• Sinonimo/i: Dentin sialophosphoprotein, Dentin phosphoprotein, Dentin phosphophoryn, DPP2.Dentin sialoprotein, DSP
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: 2C12.3, monoclonal
• Reattività contro le specie: mouse, rat
• tecniche: immunohistochemistry: suitable
• Isotipo: IgG2bκ
• N° accesso NCBI: NP_036922
• N° accesso UniProt: Q62598
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: mouse ... Dspp(666279)

Descrizione

Descrizione generale

Dentin sialophosphoprotein (DSPP) is a protein of the extracellular matrix. It belongs to the small integrin-binding ligand, N-linked glycoprotein (SIBLING) family. DSPP is found in teeth and bone and is primarily involved in biomineralization processes in these structures. This function may be facilitated by the interaction of DSPP with multiple protein targets including DMP1, BMP2, Runx2, and NF-Y. DSPP plays a central role in dentinogenesis.

Immunogeno

Pure DSP isolated rat dentin

Applicazioni

Anti-Dentin sialoprotein, clone 2C12.3 detects levels of Dentin sialoprotein proteins & has been published & validated for use in IHC.

Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in rat mandibular tissue. (Baba, O., et al. (2004). Eur J Oral Sci. 112:163–170.)

Research Category
Cell Structure

Research Sub Category
Cytoskeleton

Qualità

Evaluated by Immunohistochemistry in mouse and rat teeth tissues.

Immunohistochemistry Analysis: 1:250-1,000 dilution of this antibody detected Dentin sialophosphoprotein in mouse and rat teeth tissues.

Descrizione del bersaglio

68 kDa calculated. Uniprot describes 2 isoforms at 64 and 70 kDa

Stato fisico

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Risultati analitici

Control
Mouse and rat teeth tissues

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable