MABN92-AF488

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor^™ 488 Conjugate

clone 20A12.1, from mouse, ALEXA FLUOR^™ 488

• Sinonimo/i: Allograft inflammatory factor 1, AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.45

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Coniugato: ALEXA FLUOR^™ 488
• Forma dell’anticorpo: purified antibody
• Tipo di anticorpo: primary antibodies
• Clone: 20A12.1, monoclonal
• Reattività contro le specie: human, mouse, rat
• tecniche: immunohistochemistry: suitable
• Isotipo: IgG1κ
• N° accesso NCBI: NP_001614
• N° accesso UniProt: P55008
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... AIF1(199)

Descrizione

Descrizione generale

Allograft inflammatory factor 1 (UniProt P55008; also known as AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1) is encoded by the AIF1 (also known as G1, IBA1) gene (Gene ID 199) in human. Iba1/AIF1 is a 17 kDa interferon-gamma- (IFN-gamma-) inducible, Ca(2+)-binding EF-hand protein. Iba1/AIF1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma. It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and macrophage activation/function. It is also shown to be expressed in microglial cells in autominnume disesase models such as experimental autoimmune encephalomyelitis, neuritis and uveitis.

Applicazioni

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor^™ 488 Conjugate is an antibody against Iba1/AIF1 for use in Immunohistochemistry.

Qualità

Evaluated by Immunohistochemistry in human spleen tissue.

Immunohistochemistry Analysis: A 1:300 dilution of this antibody detected Iba1/AIF1 in human spleen tissue.

Descrizione del bersaglio

~17 kDa observed

Altre note

Concentration: Please refer to lot specific datasheet.

Note legali

ALEXA FLUOR is a trademark of Life Technologies

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable