HTH17MAG-14K
MILLIPLEX® Human TH17 Magnetic Bead Panel - Immunology Multiplex Assay
Simultaneously analyze multiple Th17 cytokine and chemokine biomarkers with the Th17 Bead-Based Multiplex Assays using the Luminex technology, in human serum, plasma and cell culture samples.
Sinonimo/i:
Human Th17 cytokine multiplex kit, Luminex® human Th17 cytokine immunoassay, Millipore human Th17 cytokine panel
About This Item
Prodotti consigliati
Livello qualitativo
Reattività contro le specie
human
Produttore/marchio commerciale
Milliplex®
assay range
accuracy: 79-107%
standard curve range: 1-5000 pg/mL
(IL-10)
standard curve range: 10-40,000 pg/mL
(IFNγ)
standard curve range: 12-50,000 pg/mL
(IL-17A & IL-2)
standard curve range: 24-100,000 pg/mL
(IL-17 & IL-4)
standard curve range: 3-10,000 pg/mL
(IL-6 & TNFα)
standard curve range: 336-1,500,000 pg/mL
(IL-23)
standard curve range: 37-150,000 pg/mL
(IL-22 & TNFβ)
standard curve range: 488-2,000,000 pg/mL
(IL-17E/IL-25)
standard curve range: 49-200,000 pg/mL
(IL-28a & IL-31)
standard curve range: 5-20,000 pg/mL
(MIP-3α, IL-1β, IL-12 (p70), IL-15, IL-21 & IL-33)
standard curve range: 6-25,000 pg/mL
(IL-5)
standard curve range: 61-250,000 pg/mL
(GM-CSF & IL-27)
standard curve range: 7-30,000 pg/mL
(IL-13)
standard curve range: 9-35,000 pg/mL
(IL-9)
tecniche
multiplexing: suitable
Metodo di rivelazione
fluorometric (Luminex xMAP)
Condizioni di spedizione
wet ice
Categorie correlate
Descrizione generale
Th17 cells are involved in the clearance of extracellular bacteria and fungi. They are abundant in the intestinal lamina propria and function as a barrier against invading pathogens. Excessive amounts of Th17 cells have been implicated in the pathogenesis of several autoimmune diseases, including multiple sclerosis, psoriasis, juvenile diabetes, rheumatoid arthritis, Crohn′s disease, and autoimmune uveitis. In addition, Th17 cells play an important role in tumor development, progression, and metastasis, potentially in both promoting and inhibiting tumor growth.
MILLIPLEX® Human TH17 Bead Panel is a 25-plex kit to be used for the simultaneous quantification of the following analytes in serum, plasma or culture supernatant samples: GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12 (p70), IL-13, IL-15, IL-17A, IL-17F, IL-17E/IL-25, IL-21, IL-22, IL-23, IL-27, IL-28A, IL-31, IL-33, MIP-3α/CCL20, TNF-α and TNFβ.
The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.
Panel Type: Cytokines/Chemokines
Specificità
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Applicazioni
- Analytes: GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12 (p70), IL-13, IL-15, IL-17A, IL-17F, IL-17E/IL-25, IL-21, IL-22, IL-23, IL-27, IL-28A, IL-31, IL-33, MIP-3α/CCL20, TNF-α, TNFβ
- Recommended Sample type: Serum, plasma, and cell culture samples
- Recommended Sample dilution: Neat
- Assay Run Time: Overnight
- Research Category: Inflammation & Immunology
Caratteristiche e vantaggi
Stoccaggio e stabilità
Altre note
Note legali
Esclusione di responsabilità
Avvertenze
Danger
Indicazioni di pericolo
Classi di pericolo
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
Organi bersaglio
Respiratory Tract
Codice della classe di stoccaggio
10 - Combustible liquids
Certificati d'analisi (COA)
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Contenuto correlato
Immunology multiplex assays, like MILLIPLEX® assays, allow researchers to investigate more immune biomarkers simultaneously, saving time and resources. This is especially critical to immunology research, where numerous analytes play a role in different pathways.
See how MILLIPLEX® multiplex immunoassays offer researchers the ability to simultaneously quantitate a large number of human cytokines, chemokines, and growth factors, and detect human immunoglobulins against SARS-CoV-2 antigens, to better understand the immune response to COVID-19, including cytokine storm.
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