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Merck
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Key Documents

AB9352

Sigma-Aldrich

Anti-Po Antibody

Chemicon®, from chicken

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

chicken

Livello qualitativo

Forma dell’anticorpo

affinity purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Purificato mediante

affinity chromatography

Reattività contro le specie

mouse, human

Produttore/marchio commerciale

Chemicon®

tecniche

immunocytochemistry: suitable
immunohistochemistry: suitable

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Specificità

Recognizes Glycoprotein Po. Po is the major glycoprotein in peripheral myelin

Immunogeno

Synthetic peptides from human/mouse Po.

Applicazioni

Immunohistochemistry: 1:50-1:100 using 2% paraformaldehyde fixed tissues.

Immunocytochemistry: 1:50-1:100 using 2% paraformaldehyde fixed cells.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers
This Anti-Po Antibody is validated for use in IC, IH for the detection of Po.

Stato fisico

Affinity purified chicken IgY. Two different antibodies were combined to make this product. Liquid in PBS, pH 7.2 with 0.02% sodium azide.

Stoccaggio e stabilità

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. It is recommended that the antibody be stored in the dark.

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Bradley A Heller et al.
The Journal of cell biology, 204(7), 1219-1236 (2014-04-02)
The PI 3-kinase (PI 3-K) signaling pathway is essential for Schwann cell myelination. Here we have characterized PI 3-K effectors activated during myelination by probing myelinating cultures and developing nerves with an antibody that recognizes phosphorylated substrates for this pathway.
Maria Alejandra Gonzalez-Gonzalez et al.
Frontiers in neuroscience, 16, 726467-726467 (2022-06-03)
Hypertension is a main cause of death in the United States with more than 103 million adults affected. While pharmacological treatments are effective, blood pressure (BP) remains uncontrolled in 50-60% of resistant hypertensive subjects. Using a custom-wired miniature electrode, we
The 4.1B cytoskeletal protein regulates the domain organization and sheath thickness of myelinated axons.
Einheber, S; Meng, X; Rubin, M; Lam, I; Mohandas, N; An, X; Shrager, P; Kissil, J; Maurel et al.
Glia null
Andreas Flütsch et al.
Neuroreport, 27(18), 1305-1311 (2016-11-09)
Schwann cells (SCs) detect injury to peripheral nerves and transform phenotypically to respond to injury and facilitate repair. Cell-signaling pathways and changes in gene expression that drive SC phenotypic transformation in injury have been described; however, the SC receptors that
Brendan Zotter et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 42(2), 183-201 (2021-11-14)
Peripheral nerves are organized into discrete compartments. Axons, Schwann cells (SCs), and endoneurial fibroblasts (EFs) reside within the endoneurium and are surrounded by the perineurium, a cellular sheath comprised of layers of perineurial glia (PNG). SC secretion of Desert Hedgehog

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