Passa al contenuto
Merck
Tutte le immagini(1)

Key Documents

AB1846

Sigma-Aldrich

Anti-C-X-C Chemokine Receptor 4 Antibody, NT

Chemicon®, from rabbit

Sinonimo/i:

CD184, CXCR4

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(1)

About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Reattività contro le specie

human

Produttore/marchio commerciale

Chemicon®

tecniche

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

N° accesso NCBI

NM_001008540.1
NM_003467.2

N° accesso UniProt

P61073

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... CXCR4(7852)

Specificità

Recognizes CXCR4, N-terminus.

Immunogeno

Amino-terminus peptide of human CXCR4 (Berson, 1996; Leotscher, 1994).
Epitope: N-terminus

Applicazioni

Anti-C-X-C Chemokine Receptor 4 Antibody, N-terminus is an antibody against C-X-C Chemokine Receptor 4 for use in IC, IP & WB.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors
Western blot: 1-2 μg/mL. HeLa cell lysates can be used as positive control. The antibody should detect a band at 40 kDa.

Immunocytochemistry: 10 μg/mL

Immunoprecipitation

Optimal working dilutions must be determined by end user.

Descrizione del bersaglio

40 kDa

Stato fisico

Format: Purified
Protein A purified
Purified IgG in PBS containing 0.02% sodium azide.

Stoccaggio e stabilità

Maintain 1 year at 4°C, from date of shipment. Do not freeze. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Risultati analitici

Control
Skin

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Non trovi il prodotto giusto?  

Prova il nostro Motore di ricerca dei prodotti.

Raccomandato

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Nitric oxide donor upregulation of stromal cell-derived factor-1/chemokine (CXC motif) receptor 4 enhances bone marrow stromal cell migration into ischemic brain after stroke.
Cui, X; Chen, J; Zacharek, A; Li, Y; Roberts, C; Kapke, A; Savant-Bhonsale, S; Chopp, M
Stem Cells null
Stromal cell-derived factor 1alpha mediates neural progenitor cell motility after focal cerebral ischemia.
Robin, AM; Zhang, ZG; Wang, L; Zhang, RL; Katakowski, M; Zhang, L; Wang, Y; Zhang, C; Chopp, M
Journal of Cerebral Blood Flow and Metabolism null
Effects and mechanisms of blocking the hedgehog signaling pathway in human gastric cancer cells.
Gu, H; Li, XU; Zhou, C; Wen, Y; Shen, Y; Zhou, L; Li, J
Oncology Letters null
Linhui Wang et al.
Oncology reports, 22(6), 1333-1339 (2009-11-04)
Renal cell carcinoma (RCC) shows organ-specific metastasis. This may be attributed to the fact that the CXCR4 G protein coupled receptor on RCC cells mediates chemo-attraction toward stromal-derived factor (SDF)-1 secreted by target organs. SDF-1 binding to CXCR4 initiates many
Jane D Holland et al.
Cancer research, 66(8), 4117-4124 (2006-04-19)
CXCR4 is a G protein-coupled receptor of considerable biological significance, and among its numerous functions, it is suggested to play a critical role in cancer metastasis. We have investigated the expression and function of CXCR4 in a range of breast
Visualizza tutti i documenti correlati

Articoli

Acute and Chronic Inflammation: Microglia in Neuroprotection and Neurodegeneration

The term neurodegeneration characterizes a chronic loss of neuronal structure and function leading to progressive mental impairments.

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.