8.22278

Acetic anhydride

for synthesis

• Sinonimo/i: Acetic anhydride, Acetyl acetate, Acetyl oxide
• Formula condensata: (CH₃CO)₂O
• Numero CAS: 108-24-7
• Peso molecolare: 102.09
• Numero MDL: MFCD00008705
• Codice UNSPSC: 12352106
• Numero indice EU: 203-564-8
• NACRES: NA.22

Proprietà

• Grado: for synthesis
• Livello qualitativo: 200
• Tensione di vapore: 4 hPa ( 20 °C)
• Saggio: ≥98.0% (GC)
• Stato: liquid
• Temp. autoaccensione: 330 °C
• Potenza: 630 mg/kg LD₅₀, oral (Rat); 4320 mg/kg LD₅₀, skin (Rabbit)
• Limite di esplosione: 2.0-10.2 % (v/v)
• pH: 3 (20 °C, 10 g/L in H₂O)
• Punto di fusione: -73 °C
• Temp. transizione: flash point 49 °C
• Densità: 1.08 g/cm³ at 20 °C
• Temperatura di conservazione: 2-30°C
• Stringa SMILE: O(C(=O)C)C(=O)C
• InChI: 1S/C4H6O3/c1-3(5)7-4(2)6/h1-2H3; WFDIJRYMOXRFFG-UHFFFAOYSA-N

Descrizione

Descrizione generale

Acetic anhydride is a widely used reagent in organic synthesis. The reagent is effective for acetylating alcohols, amines, and thiols. Additionally, it is used in various named reactions such as the Pummerer reaction, the Perkin reaction, the Polonovski reaction, the N-oxide reaction, and the Thiele reaction. Acetic anhydride is an effective reagent during oxidation of alcohols, dehydration, ether cleavage, enol acetate formation, and gem-diacetate formation.

Applicazioni

Acetic anhydride is used:

• In the solvent free acylation of 2-methylfuran to 2-acetyl-5-methylfuran in presence of hydroxide fluorides catalyst.
• As a catalyst in the synthesis of 3-arylideneisobenzofuran-1(3H)-one derivatives from phthalic anhydride and quinoline derivatives.
• In the preparation of hyperbranched poly ethoxy siloxanes by condensation reaction with tetra ethoxy silane in presence of an organotitanium catalyst.

Risultati analitici

Assay (GC, area%): ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C): 1.080 - 1.082
Identity (IR): passes test

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS05,GHS06
• Avvertenze: Danger
• Indicazioni di pericolo: H226 - H302 - H314 - H330
• Consigli di prudenza: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 120.2 °F - closed cup
• Punto d’infiammabilità (°C): 49 °C - closed cup